The Ultimate Guide to DMT & Harmalas

https://www.dmt-nexus.me/forum/default.aspx?g=posts&t=39239
DMT-Nexus Wiki:Health and Safety


Table of Contents

1. About
- 1.1 Disclaimer

2. Safety
- 2.1 Set and setting
- 2.2 Dietary constrictions
- 2.3 Dosage
- 2.4 Metal stability
- 2.5 Addictiveness
- 2.6 Law

3. Botanicals
- 3.1 Active alkaloids
- 3.2 DMT Plants
- 3.3 Harmala Plants
- 3.4 Extracting
- 3.5 Dosages
- 3.6 Combinations

4. Oral
- 4.1 Ayahuasca Brew
- 4.2 Syrian Rue
- 4.3 Vinho da Jurema
- 4.4 Formosahuasca
- 4.5 Pharmahuasca
- 4.6 Safety oral

5. Smoking
- 5.1 Burning
- 5.2 Vaporizing
- 5.3 Enhanced Leaf
- 5.4 Changa
- 5.5 Dabbing
- 5.6 e-Cigarettes
- 5.7 Safety smoking

6. Other
- 6.1 Sublingual
- 6.2 Insufflating
- 6.3 Nasahuasca
- 6.4 IV
- 6.5 Intrarectal
- 6.6 Safety other routes

7. Additional Info
- 7.1 Making Changa
- 7.2 About dabbing
- 7.3 e-Cigarette info
- 7.4 DMT Extraction

8. Sources


1. About

Lots of information about DMT can be found online. Unfortunately most of it is dispersed and some simply wrong. In order to promote efficiency and decrease chances of a bad experience I bundled everything you need to know into one topic for easy reference. Written with the intent that when someone new reads through it, all necessary know-how is obtained to efficiently produce and use DMT. This post covers all the basics and terminology used on DMT-Nexus. Hopefully it helps to reduce time answering frequently asked questions and gets everyone up to speed.

1.1 Disclaimer

Use

The goal is education. Either to those who already have an intention to try something for the first time, or those who seek more info. I do not intent to influence anyone into doing anything written here. Follow at your own risk and respect your countries laws. Please read everything regarding health and safety with care and attention. You are free to distribute this text. Please always include a link to this page (source). This post will be updated from time to time. Linking back makes sure that the everyone has access to the latest version. Out of personal interest, if you can - let me know where you are sharing.

Warning: DMT-Nexus is anti DMT "spreading". Doing big extractions, selling DMT, handing out to people normally not inclined to use it, etc. Spreading of the message of psychedelics itself through superficial YouTube videos showing use or extractions can also cause a lot of damage to the community (as happened with salvia) and is frowned upon. See the "Attitude Page, section 2.10" in the DMT-Nexus Wiki for more info. Please treat all knowledge on DMT-Nexus with respect.

Validity

I've done my best to make valid statements based on the information at hand by analyzing its credibility. However, some info is based on limited accounts. It would be good to have additional people share their experiences or test and report findings to check the validity of things stated only by a few. Do not regard anything written as absolute truth! This is to be used as a guide and reference only. Try to obtain more information before taking any action. Double check and verify. Don't hold me or Nexus responsible if something does not go according to expectation. This guide is meant to reflect the general opinion of the Nexus community. If anyone has anything to add do post and I will update. Sources are topics from the Nexus-forum, Wiki, FAQ, DMT Handbook. Links to sources and additional information per section can be found in Chapter 8.


2. Safety

2.1 Set and setting

My personal recommendation is to start out by finding a trustworthy and experienced Ayahuasaca ceremony. This might not be easy, but if you manage you will learn how others create the right circumstances to work with the plants.

Ayahuasca is commonly done in a ceremonial setting organized by various /tribes /communities in numerous countries. Traditionally it is used by indigenous people to treat various illnesses. Their shamans posses knowledge passed on from generation to generation on how to use the plants to heal and progress. They are able to create the right set and setting, control the energy level, steer away from bad experiences and keep bad energies out. Sacred chants play an important role. This enables non experienced people to dive deep. In fact most Ayahuasca regulars say they would never use it at home without the -protection- of a Shaman.

When using outside of an organized ceremony: create a proper set and setting. Be at home or somewhere private. Alone is not recommended. Be together with people you trust and know are up to it. Take your time to prepare and to recover. For oral use leave the day after free. Avoid use in public places. If you insist on doing it outdoors, choose a quiet place where you won't get disturbed (nature).

Be sure to protect yourself as well as DMT's reputation: be safe and don't act irresponsible while on it; don't get caught being on it in unlawful situations such as driving under influence; etc. Keep in mind that most governments and media seek reasons to give hallucinogenics a bad reputation. Don't give them any. Treat the plants /compounds and yourself with respect. Don't worry, the experience in itself is so powerful that it will teach you how to do so. This can be painful. DMT is not for everyone. It can be the most profound experience you can have, or the most terrifying one. Listen to your intuition if it's the right time. If it is, mentally prepare for an experience which could change your outlook on life.

2.2 Dietary constrictions

Harmala alkaloids are RIMA's. Meaning dietary restrictions can be largely ignored as they do not contain MAOI. It is still not advisable to consume large quantities of alcohol or tyramine containing foods such as old cheese. Preferably diet 24 hours prior and after. This will also clean your body for a better experience. It is recommended to eat properly (not stuffing yourself) around 4-5 hours prior to the journey. This will give you sufficient strength and still a relative empty stomach when you start.

Although RIMA's are generally safer than MAOI's, they still have highly dangerous interactions when combined with almost any antidepressant, stimulant or SSRI drug. Orally consuming RIMA's can be extremely dangerous combined with psycho-actives such as antidepressants, stimulants and SSRI drugs. It can cause serotonin syndrome or hypertensive crisis, possibly resulting in death! When you are on this type of medication you have to quit at least one month before taking any form of Harmalas! This applies to all ROA.

2.3 Dosage

If you are using a new batch of plant material for the first time, always start off with a low dose and work your way up in small increments. The optimal dosage may vary significantly from person to person. It is not possible to overdose on DMT and RIMA. There is no direct (neuro)toxicity on the body. However, too much RIMA can make you very sick physically. Too much DMT can be very intense mentally. If this happens, don't worry and just remember: you will recover.

2.4 Metal stability

Ayahuasca is a therapeutic experience and is known to cure depressions, stop addictions and promote mental and physical health. However, care should be taken with people suffering from mental disorders and instabilities such as schizophrenia and psychotic tendencies. The chaotic nature of the experience can trigger an escalation of mental issues. This can lead to an increase of psychological problems in individuals susceptible to such problems. You must be able to rely on yourself to have sufficient mental stability and/or strength to undergo the experience and face what surfaces.

2.5 Addictiveness

DMT and Harmalas are neither psychologically nor physically addictive. Ayahuasca is regarded as a medicine and is actually used for treating various addictions with great success. DMT / Ayahuasca can be a hard and/or intense experience with suffering such as psychical pain or emotional self confrontation. The goal is therapeutic effects felt afterwards. This makes Ayahuasca a medicine. As such its use is based on a healthy intension. As happens when coming in close contact with nature, connecting deeply with others, or experiencing deep self knowledge, such intense experiences usually lead to something constructive. Rule of thumb: the more you suffer during, the bigger the benefit afterwards. The opposite applies to recreational drugs - hence this is not.

2.6 Law

Warning: DMT and Harmalas are outlawed in most countries. Possessing it or plants containing it is illegal.

It is interesting to think about why DMT and other ethnobotanical plants found in nature are banned by our society. A criteria for a substance to become a class 1 scheduled drug in the States is that it must have zero therapeutic use. However, Ayahuasca has been used for thousands of years to treat people. Anyone who used it can tell you how it changes you for the better. Improving your outlook on life, increasing self acceptance and changing the way you interact with others - with more love and attention. Let alone the neurological benefits that science is now unraveling, helping with depressions etc. Further more, DMT and Harmalas have no (neuro)toxic effects on brain and body. Why the amount of effort put in indoctrinating citizens against ethnobotanical plant use through media and politics? Is it pure ignorance, pharmaceutical lobby, war on consciousness, suppression of thought? Who knows.. On a positive note, we seem to be entering an era of psychedelic renaissance where science is identifying the medicinal properties of these forbidden fruits.


3. Botanicals

3.1 Active alkaloids

DMT

DMT (N,N-Dimethyltryptamine) is a psychedelic compound of the tryptamine family. Its presence is widespread throughout the plant kingdom. DMT occurs in trace amounts in mammals, including humans, where it putatively functions as a neurotransmitter. The significance of its widespread natural presence remains undetermined. DMT is the only psychedelic known to occur naturally inside the human body. When ingested, DMT acts as a psychedelic drug. Depending on the dose and method of administration, its subjective effects can range from short-lived milder psychedelic states to powerful experiences; these are often described as a total loss of connection to external reality and an experience of encountering indescribable spiritual /alien realms. DMT is called the "spirit molecule" because of its ability to allow humans to transcend states of consciousness.

Harmala Alkaloids

To be able to take DMT orally it needs to be combined with a MAOI (Monoamine Oxidase Inhibitor) or a RIMA (Reversible Inhibitors of Monoamine Oxidase A). The role of a MAOI /RIMA is to stop your digestive system from breaking down the DMT molecule. When administering DMT orally, it is the digestive tract where you first and foremost want to have the strongest MAO inhibition. The way to achieve this is by orally consuming MAOI's or RIMA's prior or together with DMT.

The active enzyme inhibitors in plants commonly used in combination with DMT are the Harmala Alkaloids. Harmalas mainly consist of Harmine, Harmaline and Tetrahydroharmine. Besides stopping the breakdown of DMT they also have a psychedelic effect on their own.

Harmala alkaloids are RIMA's. RIMA's selectively and reversibly inhibit the enzyme 'monoamine oxidase A' (MAO-A). Because of their reversibility and selectivity, RIMAs are safer than MAOI's. RIMA's are unlikely to elicit tyramine-mediated hypertensive crisis. This means that a special diet does not need to be so strictly adhered to as with MAOI's. Eating excessively large amounts of tyramine-containing foods within 24 hrs is still not recommended. Research "RIMA vs MAOI" for more info.

DMT + Harmalas

Other than allowing for oral ingestion of DMT, the combination of DMT + RIMA results in a synergy of effects. DMT triggers RIMA effects which don't arise without the use of DMT and visa versa. This is why smoking DMT + RIMA is different than smoking DMT without.

3.2 DMT Plants (The Light)

Psychotria Viridis (leaves)

Aka: Chacruna, Sami Ruca
Actives: 0.1 - 0.6% DMT, MMT, MTHC

Viridis is the most traditional of all Ayahuasca admixture plants. The effects of Viridis are considered to be clean and friendly. A very "green energy". Viridis is sometimes reported to be too weak. But when it works it can have a very immerse effect with deep mental dimensions. The leaves of the plant are harvested. Due to leaves being light and the small percentage of actives in them, relatively quite a large pan needs to be used to be able to boil the brew in.

Mimosa Hostilis (root bark)

Aka: MHRB, Jurema Preta
Actives: 2.0% DMT

Mimosa is mostly of a more consistent quality and is said to give more visual effects than Viridis. Others report it makes them feel darker and more toxic. Mimosa seems more compatible with Syrian Rue than with Caapi. Due to its stable consistency and purity Mimosa is usually the plant of choice for DMT extraction.

Mimosa tea can also be extracted in cold water (CWE) for oral use. In theory Mimosa contains its own beta-Carbolines which get destroyed by heat. This means CWE results in more intake of RIMA's. It is also theorized that the extra non DMT alkaloids in Mimosa are either a substance with MAOI properties, or substances that potentiate DMT. This would explain why a CWE can be drank without Harmalas (much larger dosage required). However, nothing has been found to be an MAOI within Mimosa. Some speculate that Yuramine or a degraded Yuramine product may be the culprit. In addition to the Yuremamine and miscellanious beta-barbolines it's also possible that some of the bark's saponins, sterols, or chalcones are contributing to the CWE psychoactivity in some fashion.

The effect of CWE is reported to be much better (cleaner) than boiled MHRB brew.

Diplopterys Cabrerana (leaves)

Aka: Chaliponga
Actives: 1.7% DMT, 5-MeO-DMT, 5-HO-DMT

Although less potent by weight than Mimosa, Chaliponga has the most powerful psychological effect. It is markedly different from Mimosa and Viridis. A common believe is that this is due to the presence of 5-meo-dmt. But in fact there is no significant 5-meo-dmt content in chaliponga. It seems to be more a rumor than anything else, as it has only been found in traces so far.

Acacia Confusa (root and bark)

Aka: ACRB, Formosahuasca, Chinahuasca, Asian ayahuasca
Actives: 1.4% DMT, 1.2% NMT

Acacia Confusa is a tree native to South-East Asia and containing large amounts of psychoactive tryptamines in its bark and root bark. It contains both DMT and NMT. In proportion, more DMT in the bark, more NMT in the root. It also contains Alkaloids with RIMA properties. Being active without the addition of Harmala alkaloids it is reminiscent of reports of cold water extracted Mimosa. People have reported difficult to handle journeys and very deep experiences with scary entry stages. A plant to treat with a lot of caution and respect. It's very important to start with a low dosage before working your way up.

3.3 Harmala Plants (The Force)

Banisteriopsis Caapi (vine)

Aka: Ayahuasca, Caapi, Yaje
Actives: +-2.0% Harmala alkaloids (0.31-8.43% Harmine, 0.03-0.83% Harmaline, 0.05-2.94% Tetrahydroharmine

Banisteriopsis Caapi is a South American jungle vine of the family Malpighiaceae. It is the most commonly used plant to prepare Ayahuasca. It has a a long history of entheogenic uses as a medicine and "plant teacher" among the indigenous peoples of the Amazon Rainforest. The shamans of the indigenous western Amazonian tribes use the plant in religious and healing ceremonies.

Banisteriopsis Muricata (vine)

aka: Red vine
Actives: Same profile as Caapi

A nexus user performed a chemistry test and found the alkaloid profile of B. Muricata to be very similar to standard B. Caapi. Users report Muricata to be similar in effect yet more potent - requiring much less material for a solid dose. Some say Muricata is equality potent, this could have to do with batch quality.

Syrian Rue (seeds)

Aka: Peganum Harmala, Harmal, Rue
Actives: +-5.0% Harmala alkaloids (0.44%-4.30% Harmine, 0.25%-5.60% Harmaline, 0.10% Tetrahydroharmine

Sirian Rue is of the family Nitrariaceae. It is native from the eastern Iranian region west to India. Rue may have been used as an entheogen in the Middle East in ancient times. It can be used as an analogue of Caapi to create an ad hoc of Ayahuasca brew.

Passiflora (flowers)

Aka: Passion flowers, passion vines
Actives: unknown (0.2% in P. incarnata according to some studies)

Some Amazonian Ayahuasqueros add Passiflora to Ayahuasca as an admixture. They call it Chontay-huasca and say it adds color to the visions. Passiflora is said to be too weak an RIMA to be used on its own. But the studies on which this is based used poor extracting techniques. In theory some Passion flowers contain more RIMA than stated and could be used as enzyme inhibitors. However, more research is needed.

2.4 Caapi varieties

Ethnobotanical suppliers use color names to describe the Caapi being sold. Usually they are named by the local /mestizos /indigenous people. Their use of colors to describe the types of Ayahuasca is based on the nature and character of the visionary experiences as well as the physical color of the plant.

The problem is that there is no consensus regarding the classification of different Caapi vines, so some indigenous people may recognize 2 types, in another tribe they may recognize 10 types, and so on. These types may overlap or they may even be in contradiction with each other. Also botanists would not necessarily agree with those types, as sometimes classification from indigenous people is not based on how a plant looks, but also on its effects, purpose, etc. Different ethnobotanical suppliers seem to stock different varieties of Caapi. In fact, some of what is sold as red, white /whatever may even be of a different genus/species altogether.

Some Caapi's have very similar alkaloid/chemical component even if they have different names. Others may have quite different content even if they are named the same. The difference can be in ratio of alkaloids or total alkaloid yield. Don't believe in generalizations saying each Caapi color has the same strength and effect in different vendors. Check the suppliers section and see if the vendor has been reviewed.

Most generalized categorizations of Ayahuasca are not in line with research performed by members of the Nexus. For example: most black Ayahuasca sold was NOT found to have any Harmalas or related alkaloids and has been identified as Alicia anisopetala. Banisteriopsis Muricata (red Ayahuasca) has the same alkaloid profile as banisteriopsis Caapi. For an in-depth analysis on differences in alkaloid contents between various types of Ayahuasca see: "The Caapi Analysis Thread" by endlessness.

3.4 Extracting

In most cases eating plants raw is not desirable or possible. The indigenously used plants above are traditionally boiled into brews using water as a medium. The active alkaloids dissolve in water. Reducing the water to a low level makes it easy to consume. The plant material remaining is depleted of actives and gets discarded. Traditional water boils are hence to be considered an extraction technique (a human innovation). By using modern knowledge and technology, plants can be extracted further. This results in isolated compounds in the form of powders or crystals. Plants containing DMT can be extracted to obtain isolated DMT-salt/freebase. Harmala plants can be extracted to obtain isolated Harmala-salt/freebase. Various chemicals can be used to achieve this.

Advantages

- Constant potency and accurate dosages (scientific)
- Enables other routes of administration such as pills and smoking (extended usage)
- Eliminates plant impurities /undesired material (purity)

Disadvantages

- Working with unhealthy products such as acids and petrochems (know-how)
- Risk of chemical contaminated yield (skill)
- Requires effort and know-how (time)
- Removes full spectrum miscellaneous actives /symbiotic plant content (effect)

Extraction paths

Below is a summary of what is more extensively covered in Section 7.4 below.
Also, see links to sources in Chapter 8.

- Acid/Base (A/B)
Acidification (< 4 pH) helps to release the active alkaloids from the plants into the water. Basing (> 11 pH) converts the salt form of DMT into DMT-freebase. A non polar solvent (NPS) is added (eg. Natha) to "pull" (move) the DMT from the basic solution into the NPS which floats on top of the basic solution. The NPS is separated and evaporated dry leaving DMT behind (or frozen lowering the saturation).

- Straight To Base (STB)
The STB path is similar to A/B. The only difference is that the acidification step is left out. Because of this the Basing step is extended to make sure all DMT leaves the bark and gets converted to DMT-freebase. Some 'dry teks' consist of mixing DMT with a bit of water and adding lye, lime or washing soda (high pH). Then leaving to dry for further separation and clean-up.

- FASX
Employs the solubility of freebase DMT and the insolubility of DMT-Fumarate in various solvents. When freebase DMT is dissolved in a solvent and Fumaric acid is added, the dissolved freebase DMT salts out as DMT-Fumarate (the only solid DMT salt). This enables easy separation without the need of evaporating /freezing. DMT salts are very stable (suited for long term storage), are used for oral ingestion and can be converted to freebase DMT for smoking.

- Eco Teks
To counter the disadvantages of using chemicals eco friendly teks such as "Extracting DMT with ethanol, vinegar and sodium carbonate" use household food-grade products only.

Best MHRB tek for newbies

"Cyb's Hybrid ATB 'Salt' Tek" (see sources) is favored for its easy procedure and high yield.

Best ACRB tek for newbies

To extract Acasia follow "ACRB TEK 100g "PICS" (see sources).

Jungle spice

Jungle Spice is the product resulting from an extraction of MHRB using a solvent more polar than Naphtha (Xylene, Toluene, d-limonene, etc). Jungle Spice is smoked or vaped like freebase DMT. Use similar dosages.

Some people claim jungle spice to be stronger or produce a different experience than pure DMT. This may be self-suggestion. It may also be that the inactive oils/impurities present in jungle spice somehow protect DMT from heat, making a more effective vaporization. It may also be that the beta carbolines together have a synergistic effect with DMT making a stronger experience. Or it may be that these beta carbolines would only really be noticeable if they were in a larger quantity as is the case with some Acacias. It may also be a mixture of any or all of the above possibilities.

3.5 Dosages

Below is an summary of dosages and combinations of the routes of administration covered in the next chapters.

Oral brew dosages

Caapi dosage: light 50g, moderate 100g, strong 150g
Muricata dosage: light 15g, moderate 30g, strong 45g
Syrian Rue dosage: light 2g, moderate 3g, strong 4g

Mimosa heated dosage: light 3-5g, moderate 5-7g, strong 7-10g
Mimosa CWE dosage: light 1g, moderate 3g, strong 5g

Viridis dosage: light 25g, moderate 50g, strong 75-100g
Chaliponga dosage: light 7g, moderate 10g, strong 15g
Acacia dosage: light 5g, moderate 10g, strong 15g

Harmalas extract dosages

Harmalas oral dosage: 100-250mg
Harmalas smoking dosage: 20-30mg
Harmalas sublingual dosage: 20-40mg

DMT extract dosages

DMT oral dosage: 30-200mg DMT in salt form
DMT vaping dosage: 15-30mg freebase DMT (efficient)
DMT smoking dosage: 20-40mg freebase DMT (less efficient)

3.6 Combinations

Oral plant brew combinations

Mimosa and Rue are said to compliment each other better than Mimosa and Caapi.
Caapi seems to go very well with Viridis and Chaliponga.
Banisteriopsis Muricata is said to go very well with Acacia Confusa.

DMT / Harmalas combinations and time delay

Oral Harmalas and oral DMT (Ayahuasca /Pharmahuasca): at the same time, or wait 10-20 min
Oral Harmalas and smoked DMT (Vaporhuasca): wait 45-60 min
Smoked Harmalas and smoked DMT (Changa): at the same time or straight after
Sublingual Harmalas and smoked DMT (Linguahuasca): wait 20-30 min

4. Oral

4.1 Ayahuasca brew

Ayahuasca is any brew made with the Ayahuasca vine (Caapi). Ayahuasca has to have the Ayahuasca vine in it, or it's not Ayahuasca. Adding a DMT containing plant to the brew is just one of many possibilities. This topic will focus on this combination only. Pharmacologically, Ayahuasca contains the necessary enzyme inhibitors that allow DMT to be orally active.

Preparation

The standard way of brewing is to first of all have the material powdered/grinded or pounded as fine as possible. Then:

Place the plant material in a stainless steel pan. Never use aluminum - it dissolves in acidic solutions. Insert more than enough water to totally submerge all the plant material (important!). Preferably use mineral or distilled water. Tap water can have too high pH and diminish yields/potency. Boil on low fire (simmer) for around 3 hrs. Filter the brew (with an old T-shirt) to separate the liquids and solids. Store the liquid separately. Add fresh water to the solids and boil everything again for 3 hrs. Do this for a total of 3 times. Put the liquid from all boils together. Reduce the liquid on low fire/simmer to a manageable amount, like for example 70ml per dose.

Option 1: Some state that adding acid to the brew will increase the potency (specially for non-powdered plant material). This is not strictly necessary (and neither the traditional indigenous way), specially if your plant is finely powdered as Alkaloids in the plant are naturally in water-soluble form. Adding acid will make the taste much worse. Don't use lemon as it is said to taste horrendous. Some use phosphoric acid, or Vitamin C crystals. White distilled vinegar is said to leave the least amount of taste (ACV tastes far worse). One tablespoon per liter of water should be more than plenty. Prepare for a fouler taste. If you can afford it buy a water distillation device. When distilled water is left standing open for several days, the pH will drop. This results acidic water with in no taste degradation and best purity.

Option 2: Use egg whites to soak up the tannins that cause bad taste and nausea. Egg white are used on Caapi and Mimosa. Other plants don't need it. Opinions vary: some report loss of potency, others don't. Some say the brew must be made acidic in order not to loose potency. Ether: add raw egg white to the unreduced boil and let it harden; or fry egg white into a flat pancake and add this to the unreduced boil. Some keep it in short, others for an hour. Filter and discard the egg white.

Option 3: Soak the left over plant material in vinegar for a day, then freeze and thaw it, then boil it for another hour or two. This should have a significant amount of alkaloids, which can either be extracted by basing and filtering like the Easy Caapi Extraction Tek. The alkaloids can be added to the main brew or consumed separately in some other occasion. If you choose not to extract, it will taste too bad to consume orally due to the vinegar. Slowly base it with sodium carbonate until it stops bubbling and/or reaches a pH of around 6. This should make it taste better.

The RIMA containing plant can be boiled together with the DMT containing plant, but specially if its the first time with a particular plant batch, its recommended to brew the two separately. This way you can find out the potency of both plants by drinking a small amount.

Administration

Traditionally the DMT and RIMA brews are combined into one drink. Depending on the strength and effect, additional dosages are taken over several hours. Caapi seems to go very well with Viridis and Chaliponga.

Tip: Eating something light just prior/after drinking the brew activates the stomach. If your stomach is empty chances are it will not digest the brew. There are plenty reports of people who don't feel effects, give up, have some food and find themselves in for a surprise.

Dosage

Banisteriopsis Caapi: light 50g, moderate 100g, strong 150g
Banisteriopsis Muricata: light 15g, moderate 30g, strong 45g
Psychotria: light 25g, moderate 50g, strong 75-100g
Mimosa: light 3-5g, moderate 5-7g, strong 7-10g
Chaliponga: light 7g, moderate 10g, strong 15g (some people report they need +20g)

Effect

Ayahuasca brew usually contains a relatively high ratio of Harmalas to DMT. The Harmalas and other spectrum of unknown actives in the vine are seen as medicinal. Traditionally DMT is only considered an activator. In modern times higher ratios of DMT are common due to the demand for visions. Not a bad thing perse, maybe a compensation for Western societies suppressed spiritual history. Learning that visions are not the main thing is part of the process.

High ratios of Harmalas cause heavy body loads. Yet the physical struggle is said to have healing properties. The mental struggle is accompanied with therapeutic insights. By not making DMT overwhelm the experience, you stay in your personality domain - focusing on life in this dimension. Some say Ayahuasca makes them look at life and see what needs to be fixed, now, instead of looking back at the end of it when it's too late.

Onset: 30 minutes - 1 hour
Peak: 2 - 6 hours
After Effects: 2 - 8 hours

4.2 Syrian Rue tea

Syrian Rue seeds are RIMA's and can be combined for their MAO effects with any DMT plant brew. As can it (just like Caapi etc.) be used in conjunction with other routes of administration.

Preparation

Syrian Rue is easy to prepare. Simply simmer (don't boil) the desired amount of ground up Rue for about 20-30 minutes and strain it. You can also do three 10 minute steeps (no cooking, no evaporation), combine them and if needed simmer down to say 100ml/dose. An acid such as lemon juice can be added to the boil. Grinding the seeds prior use could increase potency and worsen taste.

Administration

The Rue tea is consumed orally combined with DMT. Mimosa and Rue are said to compliment each other well, as does Acacia.

Dosage

Syrian Rue seeds: light 2g, moderate 3g, strong 4g

Effect

Low dosages only have RIMA effect. High dosages cause a intense psychoactive effect.

Rue and Caapi have different ratios of Harmalas. Rue usually has a lot of Harmaline and little Harmine. Caapi usually has a lot of Harmine and little Harmaline. Caapi has much more Tetrahydroharmine than Rue. Each also has an unknown amount of other alkaloids /actives. This contributes to a difference in effect. As well as set and setting, dosage, natural variability, and one's expectations to the plants effects.

Tastes of which is "better /nicer" seem to differ. Probably due to expectations and personal preference.

Some report feeling more ill with a heavier body load from Rue compared to Caapi. Others say that those who do should simply decrease their dose of Rue. Some consider Caapi to be more meaningful and deep than Rue. Others say that such statements are based on superstition as Caapi is traditionally used by the indigenous cultures of South America where Rue doesn't grow.

An interesting comparison is given by those who consider Caapi to be more feminine and Rue more masculine. Caapi is a caring and guiding mother. She has the power to steer the DMT in her direction of choice, even blocking the experience if she sees fit. Her presence and guidance is felt very strongly. Rue is more forgiving when it comes to letting the DMT do its thing. This can be a good thing for those who wish to experience strong DMT effects, but it can also be overwhelming as less guidance is felt. Its manly energy is only vaguely present in the background compared to the loud motherly voice of Caapi. Rue's teachings can be raw and direct, yet intelligent in its own way.

Finally, some report that the combination of both is better than each on themselves.

Warning: At higher dosages Rue has more MAOI effects (as opposed to RIMA at lower dosages). This means special care should be taken on diet restrictions in order to avoid headaches or worse.

4.3 Vinho da Jurema

Vinho da Jurema (aka: Jurema Preta) is a cold water extraction (CWE) of Mimosa for oral use. It can be consumed without Harmalas. However, its potency will be greatly reduced so it's recommended to combine it.

Preparation

- Put some Mimosa in a small jar
- Pour some cold water in it
- Shake it up a few times throughout the day
- Let it settle for a few days in a sealed container
- 3-5 days seems enough for most of the particles to sink to the bottom
- Poor out when the solids sink and it's easy to filter
- Optional: repeat another CWE pull /boil it /extract with DMT tek

Mimosa contains Yuremamine, a new class of phytoindoles. Yuremamine is said to be responsible for Mimosa's own MAOI effect. Heating destroys the Yuremamine and its build-in activation. Acid also destroys the Yuremamine, don't add any. Tap water can be used, but distilled (or at least filtered) water is better. No heat, no acid, no chlorine.

Administration

Drink with Harmalas.

Dosage

MHRB CWE: light 1g, moderate 3g, strong 5g (combined with Harmalas)
Some report dosing 8-12g with Harmalas. Always start low!
Without Harmalas: 10-30g MHRB

Effect

Those who have tried both say they prefer CWE over a hot brew: CWE effects feel the most clean - the sense of pure clean spice. Cooking it seems to diminish it's particular magic. Cooked Mimosa also fights the digestive system quite a bit more. If properly decanted, Mimosa isn't much more nauseating than Pharmahuasca. CWE is more sedating than standard Ayahuasca. The extra alkaloids seem to have a pain killing and sedating effect.

When free of solids CWE is said to taste much better than boiled MHRB.

4.4 Formosahuasca

Formosahuasca is a brew made of Asacia Confusa as the active DMT plant. It is also known as Chinahuasca or Asian ayahuasca. There are reports that Confusa may have a traditional history of use as an entheogen by the original peoples of Taiwan. Today it is currently used in Chinese medicine with whispers that the old herbalists know that it can take one to another world.

Preparation

- Make Syrian Rue tea (see above)
- Steep Acacia root bark in three 1 hour boils (no cooking, no evaporation)

Note: Muricata can be used instead of Rue - said to combine well (Taohuasca).

Administration

Drink the Rue first, 20-30 minutes later the Acacia. Or drink at the same time. Note that Acacia can also be consumed without Harmalas. The dosages will be higher for effects to be felt.

Dosage

Syrian Rue: 2-4 grams (start low)
Acacia: light 5g, moderate 10g, strong 15g

Note: Acacia dosage reports vary greatly. Some report using +30g. Probably depends on batch quality. Until you're familiar with your bark - experiment with low doses first: 2-3g - 4-5g.

Effect

Users reports having been through extremely blissful states of peace and harmony and overwhelming hard to handle experiences on big doses. NMT has its own effect.

4.5 Pharmahuasca

Pharmahuasca (Pharma) is a pharmaceutical version of the entheogenic brew Ayahuasca. Instead of using plant material, extracted Harmalas and DMT is used. The advantage is that extracted Alkaloids enable to accurately dose the Harmalas and DMT levels. Each traditional brew can have different strengths due to batch variations and cooking quality differences. Pharma is therefor great for accurate dosing and experimentation. The down side is that it takes know-how of how to extract. Luckily Nexus is here to help with plenty of extraction teks.

Harmalas preparation

Harmalas needs to be extracted from plants. There are numerous teks on how to do this. Caapi contains +-2% Harmalas, so from 10g of Vine you can extract +-200mg of Harmalas. Rue contains +-5% Harmalas, so from 5g of Rue you can extract +-200mg of Harmalas. Harmalas can also be taken as a pure isolated form of Harmine or Harmaline. Most online vendors sell Syrian Rue Harmalas extract (around 50/50 Harmine/Harmaline). Harmalas Freebase is not water soluble while Harmalas HCL is. Both can be used for pharma. HCL is said to be more suitable for long term storage.

Harmalas dosage

Usually a dose of one of the following is taken: 200mg of extracted Caapi /Rue full spectrum Alkaloids; 100-150 mg Harmaline; 150-250 mg Harmine. Any of these can be combined with 150-250 mg Tetrahydroharmine. As a rough guide, 100-150mg of Harmalas will be sufficient for most people. 200mg is considered a strong dose. Some people need doses up to 400mg. Preferably one should aim for a threshold dose. Everyone is different so you must experiment to find your own optimum dose. Take you time and increase slowly. Keep in mind that high Harmalas dosages can lead to nausea and stomach cramps. Vomiting is normal and considered therapeutic in Ayahuasca ceremonies. But too high a dose of extracted Harmalas can make you extremely sick.

If Caapi contains +-2% Harmalas, 50g of Vine contains +-1000mg of Harmalas. Meaning, one dose of Caapi brew contains 5 doses of Pharmauasca! How can this be? The alkaloid content of Caapi varies so much that it’s impossible to say what’s going on. Some speculate that Caapi brew has something in it that slows or regulates the absorption of Harmalas. People also report that the duration of Pharmahuasca is shorter than traditional plant brew. Only lasted for ~4 hours instead of 8+.

Harmalas effect

Harmaline is about twice as strong as Harmine. It's more sedative while Harmine is more stimulating. Some people like the sedative effects of Harmaline and find that it helps to make a more relaxed dreamy experience. Most people however prefer the stimulating effects of Harmine. They find it makes a more clear headed experience. Most people who do use Harmaline combine it with Harmine.

Tetrahydroharmine (THH) is reported to be too weak an RIMA and does not orally activate DMT. Purposively some sellers sell a mixture of THH/Harmine labeled as pure THH. Combining THH and Harmine / Harmaline results in a clearer, more focused, vivid, enhanced, controlled experience compared to Harmine / Harmaline on its own. THH is not available in all countries.

DMT preparation

DMT needs to be extracted from plants. There are numerous teks on how to do this. For Pharma it's best to use DMT Fumarate. In order for DMT freebase to become active orally, it needs to be converted to a salt. Your stomach will do it, but most people report that it's extremely uncomfortable. Better is to chemically change it prior to intake. This can easily be done by dissolving the freebase DMT in vinegar (DMT-acetate), orange juice / lemon juice (DMT-citrate), or Coca-Cola (DMT-phosphate). Most people dissolve it in orange juice, but Coca-Cola is also excellent because DMT phosphate is one of the most potent forms of oral DMT. If you use a DMT-fumarate tek, you end up with a salt straight away and don't need to convert it. DMT-fumerate is the only DMT salt in solid form. The rest are all oily making it hard to dose and handle. However if you add DMT to an acidic liquid, you just drink the liquid (the DMT-salt is dissolved inside).

DMT dosage

Oddly enough the dose of DMT in Pharmahuasca needs to be higher than that in Caapi brew. As opposed to Harmalas for which the opposite applies. Maybe this is due to a more diverse presence of Alkaloids from the Harmalas & DMT plants. These probably have an additional effects compared to the isolated alkaloids in Pharma. Oral DMT dosages vary extremely from person to person. Some people are overwhelmed with as little as 30-40mg. Others need 200mg+ before any effects are felt (no matter what type or how much Harmalas is ingested). Strangely there is no correlation between body mass or sensitivity to smoking DMT and using other psychedelics. In general: Low: 20-50mg, mid: 50-100mg, strong: 100-150mg. Keep in mind that a high dose of DMT can be an overwhelming experience. Start low and build up slowly. Additional dosages can easily be taken. Take your time to find the optimum dose.

DMT effect

People report Pharma to be a lot of hit and miss. If you don't get over the 'threshold', you don't experience what you're seeking. Luckily additional doses of Harmalas and DMT can be taken. Always take your time and build up slow. The trick finding your "sweet spot". Example: take 150mg of Harmalas with 25mg DMT. If after one hour you aren't where you want to be, take another 50mg of Harmalas and 50mg of DMT, until you find your optimal dose.

Pharma administration

Pharmahuasca can be put in capsules consisting of DMT Fumerate crystals and powdered Harmalas (freebase/HCL). Freebase DMT can also be dissolved in an acid to form a salt to which Harmalas is added.

Tip: Eat something light just prior/after administering. This actives your digestive system out of standby mode. Some smoking DMT during the come down and say it results a very meaningful experience.

Pharma effect

It is commonly reported that the effect of consuming plants holistically is different than consuming an extract. Pharma is said to miss out of some aspects of the indigenous experience. The common argument is that the plants contain additional active alkaloids and substances other than the isolated compounds alone. And that the effect of these unknown alkaloids are lost in Pharma. Others call this superstition. They argue that the difference can be attributed to the ratio of Harmalas and DMT. In Pharma the proportion of Harmalas is usually kept to a minimum. While in Ayahuasa, a bigger proportion of Harmalas is usually present. However: if different varieties and even batches of the same variety of plants give different effects, there is probably also a difference between consuming extracted Alkaloids or holistic plants, with different effects for different individuals.

Onset: 30 minutes - 1 hour
Peak: 3 - 5 hours
After Effects: 1 - 2 hours

Time delay between RIMA and DMT

The best advice is to take DMT and the Harmalas together. This works for most people and is according to tradition. However, metabolism, diet and personal resistance to Harmalas may play a role. Also, Harmine and Harmaline might have different timing effects. You might need to experiment with a time delay if taking them at the same time does not have the desired effect for you. Maybe start by waiting 5-10 or 20 min to bind the Harmalas before taking the DMT. 30 min is probably the end of the window before the Harmalas passed through the gut into the bloodstream. Take note that if the desired effects are not felt, it might be that the dosage is not sufficient for you personally.

4.6 Safety oral

If you choose to use individually outside of an organized ceremony: create a proper set and setting and be aware of RIMA dangers (see chapter 1 Safety).

Ayahuasca ceremonies are great experiences. Unfortunately there are also risks involved. It's becoming a booming business. Especially in South America. A lot of money can be made. This questions the knowledge and skills of most healers. Some people even claim there are so called "brujo's" disguised as shamans that work with black magic and the dark side of the spirit world. In Western countries there is a growing trend of spiritual healers starting to give their own ceremonies. Some use Syrian Rue instead of Caapi and call it Ayahuasca. The disadvantage of beginners mistakes /non experience can range from the attendees missing out on getting the level of healing achieved by someone more knowledgeable. To the point that the guide is not able to cope with negative energies surfacing.

Let this be a warning but don't get scared away. If you find the right place it can be an unforgettable experiences with the finest musicians and group synergies impossible to re-create at home. Just do some research.

5. Smoking

Smoking DMT (smoalking) is a very powerful way to administer it. The onset is extremely rapid. The effects last between 3-15 min, usually around 5.
The afterglow is very short compared to other methods. You can feel completely sober in 15 minutes.

This route is a good way to discover the raw effects of DMT. It takes you to extraordinary places not easily reachable through other methods of administration. The speed and intensity can be overwhelming. Don't feel bad if you have a hard time coping and not being able to relax the first couple of times. It takes some getting used to. Even experienced smokers have 'pre-flight anxiety'. The best way to deal with this is to preload with Harmalas and start each session with a small dosage.

Some people feel they reached all they could get out of smoking at one point. Due to the short duration the journey ends before you get a change to get into it. In normal dosages the oral route is a more stretched out, slower and smoother experience - staying within the realm of your ego working on improving life. Smoking is an instant ticket to an other universe where this world and your self no longer matters. However, oral and smoking are so different they shouldn't be compared. Someone gave a beautiful description of this:

If pharma is a marathon, then vaporized DMT is a sprint.
If pharma is a deep inward journey to the center, then vaporized is a distant journey to the edges.
If pharma shows me my inner-self, vaporized shows me my higher-self.
If pharma helps me in the here and now, vaporized helps “me” in the hereafter.

To smoke DMT, you need freebase DMT. Numerous teks can be found on the Nexus how to extract DMT from plants.
For more info about DMT extraction refer to Section 7.4 and sources Section 8.

5.1 Burning

A common mistake inexperienced people make when smoking DMT is placing it in a pipe on top of herbs and lighting it up. This type of smoking leads to the break down of DMT and potential toxic nitrogen oxides from impurities. Smoking freebase is harsh, it's less healthy and there is a significant loss of actives.

An better method is the layered approach. Use a water bong. Place a couple of metal screens. Add a thick layer of ashes or thin layer of herbs on the screens. Place the DMT on top of the herbs. Add another thick layer of ashes or thin layer of herbs on top of the DMT. It is essential to go easy on the fire. Too much heat will degrade the DMT. Keep the lighter as far away as possible so that it still vaporizes but doesn't over-heat your DMT. Inhale slowly and deeply, holding in the lungs as much as possible (at least a few seconds). Exhale and repeat as desired.

5.2 Vaporizing

Vaporization occurs when a controlled temperature is applied that vaporizes the DMT without burning/combustion of any material and potential impurities. This is achieved by using a heating apparatus which distributes the heat until the DMT reaches the point of vaporization and can be inhaled. Vaporizing at a temperature around 200 degrees Celsius will make the DMT evaporate. Convection (hot air) is preferable over conduction (hot glass/pipe/material) while combustion (direct fire) should be avoided.

Preparation

People have constructed their own DIY vaporizers such as "The Machine". However, usually there is a lack of adequate buffer between the fire and the alkaloids. This often burns the DMT instead of vaporising it. Don't use glass crack pipes, conduction burns the DMT. If you can afford buy a commercially sold vaporizer known to work well with DMT. A vaporizer is either heated by flame or electrically. There are numerous vaporizers reported to work well. Search the forum and see which appeals.

The most popular vaporizer used for DMT is the Glass Vapor Genie (GVG). The best way to operate the GVG is to melt the DMT prior use into a steel pad. Hot air is sucked in through a ceramic filter above by torching and inhaling. Convection heats the pad evaporating the DMT. Use a torch lighter instead of a regular one. More heat is produced and the flame won't block the ceramic filter (carbon buildup). The Arc Turboflame comes highly recommended.

You can make a pad from a metalic cleaning scrub eg. chore boy. In terms of efficiency this is not recommended. An original pad can be bought for the VGV which fits perfectly. People report good results. Another option is to get the Volcano pad. Being made for another vaporizer, it needs to be cut to fit the GVG. The Volcano pad is less densely packed (more air flow), is flatter and can be pushed further down (more separation from the hot ceramic). The GVG pad is denser and reaches higher. This results in a smaller buffer between too little and too much heat, making it harder to operate (steeper learning curve) compared to the Volcano pad. Buy both pads to see which you prefer and cut the Volcano pad to the right size using the GVG pad as a reference. Use large scissors and make sure that every little steel splinter is off. Prior use burn each pad clean on a cooking stove until glowing red. This removes the shiny metallic outer layer.

DMT vape kit:
- Glass Sherlock VG Vaporizer
- Volcano Solid Valve Liquid Pad / VaporGenie Concentrate Pad
- Turboflame Arc Lighter

Administration

Using the vape kit mentioned above:

- hold the pad with a pair of tweezers and burn it clean on a stove from any previous usage remains
- after it cools down place your DMT on the pad and use a torch lighter to carefully apply short bursts of fire to the bottom and sides
- stop when the DMT melts into the pad making sure none of it evaporates prematurely
- insert the DMT laced pad in the vaporizer and place the ceramic back on top
- exhale all the air out of your lungs and place you mouth on the mouth piece
- while inhaling aim the lighter at the ceramic with the flame just not touching it
- move the lighter to the correct distance when the vaporizer gets hotter and smoke starts to form
- keep applying heat and inhaling until all DMT is gone, hopefully you will inhale an entire dose in one hit
- if you haven't, hold the smoke in your lungs for 10 seconds and redo

Don't worry about the torch lighter flame getting too close to the ceramic filter. The GVG manual states that this is the method to clean it when carbon build-up forms from regular lighter usage. Regular lighters are not allowed to touch the ceramic, torch lighters are.
Make sure to move the flame around. Don't hold it still on one position. Excessive heat differential could shatter the glass surrounding the ceramics. Apply heat evenly.

If the smoke is too harsh on your lungs it has burned. Hold the lighter further away to decease heat. The slower you inhale, the more the air gets heated up as it travels slower through the ceramic. Too much heat will burn the DMT, too little won't vape enough. The skill is finding the lighter distance sweat spot - which moves as the ceramic filter gets hotter.

Dosage

The following dosages are for efficient vaporization methods:
Light 10-20mg, moderate 20, strong 30mg

For less efficient vaporization techniques dosages of 40-50mg are not uncommon. Start low and work your way up by increments of 5-10mg. If you don't feel anything with 10-15mg, don't increase the dose. It means you are not properly vaping the DMT.

Effect

Vaporizing DMT is the most efficient way of smoking so less is needed. With practice and the right tool you can inhale an entire dose in one hit. It gets harder to reload as the DMT kicks in. Usually the required effort is unpleasant. One hit vaping provides a smooth entrance with ease of mind.

5.3 Enhanced Leaf

Enhanced Leaf is a method of smoking whereby one dissolves freebase DMT onto smokable herbs.

Preparation

Melt DMT into herbs.
See Section 7.1 Step 3 (Warm Water Bath Tek) for details on how to make Enhanced Leaf.
See: "A Guide to DMT Enhanced Leaf" for a extensive list of herbs known to work well.

Warm Water Bath Tek summary:
For 1g of 1:1 Enhanced Leaf place 500ml of herbs in a shotglass. Add 500mg of DMT on top. Place the shotglass in pot of hot water.
The DMT will melt into the herbs. After drying it's ready for use. DMT can also be dissolved in 96% Alcohol, IPA or Acetone.
Add the DMT solution to a smokable herb and allow it to evaporate.

Administration

Enhanced Leaf is best smoked in a bong (with water):

- while inhaling, heat until it ignites. When it does try to let it continue to burn on its own
- it is essential to go easy on the fire. Too much heat will degrade the DMT
- keep the lighter far away enough so that it will light up without over-heating your DMT
- inhale slowly and deeply. Try holding the smoke in your lungs for 10 seconds. Exhale and repeat
- you should aim to inhale 60-80 mg in no more than 3 inhalations
- keep the last inhalation in for as long as you can while sitting back or laying down in position for the journey
- having someone give you a hand with the lighter and guide you through the process is recommended
- after the second inhalation it becomes very hard to focus
- several inhalations are usually required. With a big bong you might get it all in one

Another option is role a joint (no weed) of Enhanced Leaf and a tobacco replacer:

- fill the rolling paper with a smokable herb or tobacco replacer
- place a dose of Enhanced Leaf packed together at the tip of the joint
- put a bit of tobacco replacer on top which will get lighted first
- after a few puffs the Enhanced Leaf is reached
- it only takes a few inhalations to smoke the dose this way compared to spreading it out

Dosage

Light 15-20mg, moderate 20-30mg, strong 30-40mg
That's DMT weight. For a 1:1 blend, the dosage is double the DMT.

Effect

People report Enhanced Leaf to be just as effective as freebase, easy to dose, smoke and breakthrough. It allows for experimentation with different blends of herbs. The DMT is said to amplify the effect of the botanicals, allowing to experience the power of plants you couldn't without.

5.4 Changa

Changa is Enhanced Leaf with Harmalas - a beneficial synergy. The Harmalas source can either be Caapi herbs (usually 10x extract) or isolated Harmalas alkaloids (usually extracted from Syrian Rue). There are many varieties of Changa, but like Ayahuasca the key active ingredients are DMT and Harmalas.

The basic theory behind Changa is that very small amounts of smoked Harmalas, even in the realm of 100 micrograms to 1 mg can effect as much as 50% MAO-A inhibition and beyond. Some claim that smoked Caapi extract is 100 to 1000 fold more potent than isolated Harmalas as a RIMA.

Preparation

Melt Harmalas alkaloids and DMT into herbs.
See Section 7.1 for details on how to make Changa.

Administration

Follow the same procedure as Enhanced Leaf, see above. It is also possible to put Changa in a vaporizer instead of a bong. Another option is to create Changa without DMT. Smoke the none-DMT Changa in a pipe, followed by vaporizing DMT in a vaporizer. Harmalas alkaloids can also be vaporized on their own.

Dosage

Light 15-20mg, moderate 20-30mg, strong 30-40mg
That's DMT weight. For a 1:1 blend, the dosage is double the DMT.

Effect

The effects of Changa are considered to be more deep and meaningful than DMT smoked on its own. The RIMA’s and botanicals work together to give a smoother experience. The intelligent alchemy of the combination between DMT with Ayahuasca vine gives Changa its unique nature. The effects have been reported as being similar to a short Ayahuasca trip. The duration of effects is a bit longer than that of DMT alone (factor 1.3x to 1.5x), lasting up to 12 minutes in some cases. Changa can also be used in conjunction with Ayahuasca brew to intensify the experience or revisit it during the come down.

5.5 Dabbing

Dabbing is a method of consuming concentrated oils by dropping a small amount on a hot surface and allowing it to vaporize.
If you want to learn about the basics of dabbing, refer to Section 7.2. It will teach you all the terminology and everything you need to know.

Preparation

What you need:

Rig:
A smaller sized bong with a (larger holed) single percolator and a male joint. Or buy a male-to-male cross-over.
Maintain low water level. If you already own a bong, try to use that one.

Nail:
A seasoned Quartz domeless female nail (banger) with carb cap. Same size as the bongs joint. Or buy a cross-over.
E-nails are perfect for temperature control, but more expensive. Prices should drop as time goes by.

Torch:
A large butane torch. It's more expensive than propane, but recommended for Quartz nails.
A Turboflame Arc Lighter or similar sized will be too small to apply sufficient heat.

Administration

Temperature control:
Dabbing is all about timing and technique to maximize either flavor or efficiency. It requires some experimentation and practice.

Some say heating the nail red hot and waiting for the moment it switches from glowing to colorless (maybe after 10-20 seconds) is the optimal time to dab spice. One user reports heating a seasoned Quartz domeless nail for 11 seconds and waiting 18 seconds work perfect to dab 40 mg spice in one hit with ease and zero residue. However, every single nail is different and has its own properties. You must experiment to find the optimal temperature.

Temperatures:
DMT melting point 45°C
DMT boiling point 60-80°C @ vacuum
DMT vaporises at 160°C
Electronic vapes are usually set at 200°C

Most people believe that the optimal dapping temperature for DMT is the range in which the Leidenfrost effect occurs. The Leidenfrost effect is a physical phenomenon in which a liquid, in near contact with a mass significantly hotter than the liquid's boiling point, produces an insulating vapor layer keeping that liquid from boiling rapidly. Due to this ‘repulsive force,’ the droplet hovers over the surface rather than making physical contact with it. This makes it vaporization by convection. If this is true, temperatures below the Leidenfrost effect could result in the DMT either oxidizing on the nail, or vaporizing incompletely leaving residue. While at too high temperatures the DMT will no longer "hover" on the vapor but contact the surface and burn /degrade.

The Leidenfrost effect occurs when the DMT jumps and pops like hot oil as it instantly poofs up in a cloud of vapor on/above the nail shooting droplets which poof into smoke before they touch anything. Look for this to happen. Some say the Leidenfrost effect occurs in the 250°C - 350°C range.

Other users reports that a cooler nail will cause smooth vapor and ensure nothing gets burned. They prefer having their nails too cool over too hot. A carb cap is used to compensate for lower temperatures. One user even says he sometimes loads the nail up cold and slowly heats it, waits for the vapor to start and throws his carb on.

As can be seen opinions differ. At this moment there are insufficient reports of users and experiments to say much conclusive. What you can do is start with (too) low temperatures and work your way up to (too) high temperatures. Observe the chance in efficiency (harsher vapor, less effect, more burned residue) and find your sweet spot.

Procedure:
1) Heat the nail manually with a butane torch and let it cool down to the right temperature.
2) Before loading the dmt onto the nail, start inhaling. It is essential to inhale a second or so before the dab to ensure the vapor won't escape into the air. The faster you inhale, the more the nail and the air above it is cooled and the lower the pressure gets. If you inhale too fast though, you might not have enough breath to make it to the end of the vape. You want to get everything in one breath.
3) Use a dabber to load the DMT onto the nail. Don't use a piece of folded paper, the DMT will melt into it.
4) As soon as you place the spice on the nail, place a carb cap on.
5) After about 5 to 10 seconds of inhaling you should get all the spice in.
6) Hold your breath for 10-15 seconds.
7) Warning: Blasting while holding a bong with a very hot nail is dangerous! Have someone give you a hand to place it away.

Dosage

There are various dosages reports. The required dosage comes down to efficiency (technique). Start with 10-15mg and experiment with temperature time delays and inhalation speed. If you are dabbing efficiently, increase dosage to 20-30mg (full dose).

Effects

Dabbing hits you fast and hard. Luckily you get all the vapor in one hit. People report having been hyperslapped (too intense experience). Note that burned DMT not only burns, but also influences the effect for the worse. If you feel you are having hard to handle experiences with dabbing, try decreasing the temperature.

5.6 e-Sigarettes

An e-cigarette is a device that converts electrical energy into heat to vaporize a viscous liquid composed of vegetable glycerine and/or propylene glycol (e-juice). If you want to learn about the basics of e-sigarettes, refer to Section 7.3. It will teach you all the terminology and everything you need to know.

Thanks to modern pre-made 'sub-ohm' Tank Clearomizers this route of administration is now perfectly possible. In the past, if you wanted to sub-ohm this it would require considerable skill. These days all it takes is the purchase of a sub-ohm Clearomizer and Box Mod with sufficient Watts. Sub-ohm Clearomizers make it possible to inhale a large amount of e-juice with sufficient DMT in a single puff. A couple of years ago with the pen-type vapes this was not possible.

+ Smooth flavor
No harshness, no bad taste. Depending on the concentration ratio, it can be almost imperceptible.

+ Very safe
Nothing burning, nothing to drop, break, shatter or spill. It shouldn’t even be a problem if one drops the mod.

+ No reloading
With the right DMT concentration it's a one puff hit. Also, the device will hold multiple hits, so no need to reload it after each use.

- Dosage
The disadvantage is that it's not possible to measure exactly how much DMT a puff contains. Dosing is a subjective feeling of how deep you inhale. Experienced travelers will not find this a problem. New explorers should approach with caution and awareness.

- Possible health hazards
Some studies on e-sigs suggest that toxic and carcinogenic chemicals are emitted at high power /sub ohm outputs (see sources). Other debunk these statements saying the liquid was burned dry during the tests - something which doesn't happen when smoking. However, no valid studies currently exist showing that high powered e-sigs do not emit unsafe levels of dangerous chemicals. A good bet is to keep the DMT ratio high (>1:4) so you inhale less vapor /use less power. Another good bet is to use non-flavored e-juice. Some studies claim e-juice flavors are toxic when smoked.

Preparation

What you need:

Mod Box:
For DMT 40-60 W is sufficient. A 100W box able to power a 0.5 ohm coil gives plenty of over-capacity for vaping DMT at around 50W. The batteries will run cooler than a 50W box. Look for a Mod Box with a large range eg. 10W-100W. This enables you to find your preferred spot. A good Mod Box displays voltage, watts and coil resistance. Some have temperature control if you are into that.

Batteries:
For sub-ohm vaping your batteries are the most crucial component of the setup. It's important to know what you are doing so they don't blow up. See Section 7.5 for more info. 3.7V, 30A MCD, 18650 type, IMR batteries from a well-established manufacturer are the best you can get.

Sub-ohm Tank Clearomizer:
Get a Clearomizer pre-equipped with a 0.5 Ohm OCC. If you go for less ohms, make sure your batteries and mod box can handle it. A relatively small Tank is preferred: 1.5 - 2ml. Allows for experimentation with spice concentrations. Also saves on making large amounts of spice to mix in. 2ml should be good for 10+ hits. Buy a tank that can be refilled from the top, this is convenient. Also, make sure the tank isn't prone to leakage. The 'Kangertech CL tank 2.0' is said to be good.

e-Juice:
Buy flavorless e-juice with zero-nicotine. One bottle of 100% PG and one of 100% VG. Mix PG/VG to the ratio desired (50/50 - 40/60 PG/VG). DMT can dissolve 1:1 in PG. It can not dissolve in VG. 1ml of PG can dissolve 1g DMT (1:1), so 1ml of 50/50 PG/VG can dissolve 500mg DMT (1:2). VG makes the liquid thicker and less prone to leakage. It also tastes better (less harsh).

Notes
- When you add new juice in the Tank, let it settle for 10-15 min for the wick to soak. Check the position of the wick holes. Make sure that the juice level doesn't drop below these openings or you will risk getting a burned hit.
- Experiment with the Mod Box variable Wattage output. For a 0.5 Ohm coil, around 40-50 Watts should be good.
- Harmalas could also be administered this way. A good idea would be to make a separate Harmalas tank and pre-dose on that one. At this moments there are no reports of people having tried this route for Harmalas yet.

Administration

Take a couple of deep breaths for oxygen.
Simply inhale the vape and hold your breath.

Dosage

A 1:4 DMT/e-juice ratio (250mg per 1ml) should be sufficient. Set your Mod Box to 40-60 Watts. Don't go higher. Most OCC can't run over 60W anyway. If you require more inhalations than you want, increase the DMT concentration. You can go up to 1:2 DMT/e-juice for a 50/50 blend PG/PG. Start by inhaling less to make sure its not too strong.

Effect

Flying off with the press of a button gives ease of mind compared to struggling through the learning curve of other smoking devices, or multiple inhalations. Note that this route takes a bit longer to kick in.

5.7 Safety smoking

Set and setting

Prior to smoking for the first time mentally prepare for a life changing event. When smoking create the right set and setting. Preferably do it at home together with friends or people you trust. Take turns and hear each other out. Plan sufficient time for the event. Don't use it on the street where you can get caught - keep it [DMT] low profile. Don't do anything crazy like driving - you'll ruin it for the rest.

Abuse

There have been a couple of self reported cases of prolonged periods of DMT smoking (eg. 1x per day for several weeks/months). However, cases of what you could consider abuse are extremely rare. It's good to take into consideration that anything can be prone to abuse for someone. Those who reported smoking more than they should, said they did it for a certain period and eventually stopped without issues, or due to not fancying it anymore. The vast majority of DMT smokers use it sporadically and decrease their usage over time. In general it's hard to convince your ego to do it (pre-flight anxiety), as apposed to other substances where its hard to convince yourself not to.

Potential adverse effects on the lungs

No information is known about possible (long term) health issues regarding smoking DMT on the lungs. The common argument that DMT is safe to smoke /vape is that DMT has been smoked since the 60's. Would there have been health issues, they should have been addressed. What should be considered thought is that back then most psychedelic enthusiasts rarely came across DMT. So long term effects are hard to come by. Only of late is there a larger audience for DMT and a wider pool of participants from which to draw data.

Unfortunately the lungs are not very sensitive to pain. They don't give an adequate warning about damage. Some people do report feeling pain from smoking /vaping. This pain probably reflects stimulation of pain receptors in the larger airways. The most distal parts of the lung, the alveoli, are devoid of pain receptors completely. There have been reports of people experiencing wheezing after smoking DMT. This suggests that smoking does have a negative effect on the lungs.

- Crystallization

Some people worry when they notice condensed crystal residue forming in their pipes. They worry that the deposits don't stop in the pipe and continue in the respiratory track. The condensation of the vapor is caused by the relative cold temperature of the glass pipe in comparison to the warm temperature of the vapor. The windpipe and lungs of a human are not cold enough to cause this immediate condensation and thus crystal formation. Further more, the humidified nature of the airways should not allow DMT to re-form in a crystallized fashion. Also, DMT is a biological molecule, capable of being metabolized /broken down /excreted like any other biological molecule. So even if it crystallize in your lungs, it would immediately dissolve again to be absorbed into your blood stream.

- Inhalation of hot vapor

Inhaling hot vapor can upset the function of the cilia which keep the mucus lining the airways moving. People report feeling a burning sensation on their tongue when inhaling hot DMT fumes. Suggesting that the high temperature combined with the chemical properties of DMT vapor might cause irritation /harm to lung tissue as well. If it actually does is unknown. Vaporizers reduce heat as do a water bongs. Small pipes will produce the most heat.

- Chemical irritation

Any chemical is potentially a tissue irritant. Any irritant may potentially cause inflammation. Inflammation can cause local tissue destruction and scarring. Scarring in the lungs is potentially a serious matter. Chemical irritation can be caused by pH levels. Molecules with strong redox potential can also be irritants. Theoretically, DMT might be converted to DMT-oxide when in the body and cause irritation in the lungs by doing so. Physical irritation can cause inflammation, infection and tissue damage. Whether this is the case is not known.

- Impurity's

Home extracted DMT will invariably have some contaminants. Either as a result of residual chemicals used in extracting or additional compounds in the final product. The effects to our health of burning these impurities is unknown. The yellowish color is Mimosa fats - this shouldn't do much harm.

- Burning and combustion

Some suggest that Enhanced Leave, Changa, bongs, spliffs, ect, may be more risky than using a proper vaporizer to vaporize freebase DMT. In theory by vaping you are limiting the production of toxic pyrolised organic matter. If so, then in terms of harm reduction, correct vaporisation may be the least harmful option for most people inclined to consume their DMT by 'smoking'. If you had 100% pure DMT and a device which vaporises it at only the correct temperature then this should reduce potential adverse effects on the lungs. However, the increase of toxic pyrolised organic matter produced by Changa and Enhanced Leave compared to vaping freebase, if any of significance, is unknown.

Reducing potential adverse effects on the lungs

Make sure the DMT is of as pure quality as possible. Purify /clean if needed. Don't smoke DMT fumarate. DMT fumarate contains fumaric acid, which when partially combusted can become maleic anhydride, very toxic. Try not to directly burn the DMT when vaping or smoking. Always apply as little flame for as short as possible. A good practice is to burn the content holder of your smoking device clean (also vapo's) with a torch lighter after each use. Smoke sporadically to give your lungs time to heal.

6. Other Routes

Warning: The following routes are explained for informational purpose only and are not recommended due to safety hazards!
The only safe other ROA is sublingual use of Harmalas. This is very effective combined with vaping DMT if no Changa is used.

6.1 Sublingual

Sublingual Harmalas (Linguahuasca)

Harmalas is very active sublingualy both in freebase and salt (HCL) form. In theory freebase is less effective than a salt as salts are easily soluble in water. Salts could cause more build up of saliva and accidental swallowing. Freebase doesn't have the bitterness and aftertaste of salts, yet doesn't taste great either. In the end both will do the job. It's up to personal preference.

Advantages pre-dosing with sublingual Harmalas and smoking DMT versus Changa:
- it reduces the amount of vapor/smoke you need to inhale, making it easier to get a full dose in one inhalation
- most solvents are inefficient at dissolving Harmalas which means there is always a small amount left in the dish after the leaf is dry
- changa on its own is inflexible, you can't play with the dose of Harmalas afterwards
- there is a maximum ratio of Harmalas you can insert in Change in order to have sufficient DMT and herb
- it's nice to be "Harmala'd" before launch so you are not totally sober going in - reducing pre-flight anxiety
- efficiently vaping freebase with sublingual use of Harmalas could be better for your lungs (less burned smoke vs Changa)

Preparation

See teks on how to extract Harmala alkaloids from plants.

Administration

The best is it to effectively "paint" the Harmaloids under the tongue. With powders use a finger to spread it out and rub it in. With tinctures only take a few drops at a time. Spread it by working the tongue around. Preferably swallow minuscule amounts rather than allowing saliva to buildup and dilute it. The trick is to absorb the undiluted tincture in the mouth or top of the throat, not letting it reach the stomach. Too much saliva will carry it to the stomach. In any case, do not simply pile or puddle the Harmaloids under the tongue.

Dosage

Usually a dose of 20-30mg Harmalas is taken sublingually followed by smoking DMT 20 minutes later.

Effect
Harmalas slows down the onset of DMT by 15-30 seconds, but when the peak comes it is intense. Taking a breakthrough dose of DMT after sublingual Harmalas will not extend the breakthrough by much, but will extend the come-down period. So if a "normal" DMT breakthrough without Harmalas lasts 4 minutes followed by a 5 minute comedown, with sublingual Harmalas you'll get maybe a 6 minute breakthrough and a 15 minute after glow. Sublingual Harmalas is effective for at least 2 - 3 hours after administration. Users report that smoking/vaping Harmalas or taking it sublingual is similar.

Safety

Large dosages of sublingual Harmalas can cause nausea, just like oral use. It's good to have an empty stomach. Don't eat food high in tryptamines for the day and avoid alcohol. As stated don't combine any form of RIMA administration with psychoactives such as antidepressants, stimulants and SSRI drugs.

Sublingual DMT

Extracted DMT does not rank high on effectiveness when administered under the tongue. Taking DMT this way is also quite uncomfortable. DMT freebase can cause burning sensations and is not recommended. DMT acetate can be made by adding a few drops of vinegar to freebase and is easier to take. But there are users who report having taken 100mg with no effect. Best would be to administer DMT Fumarate (converted from freebase using FASA). Some users reports success with 20-30mg DMT Fumarate combined with sublingual Harmalas extract.

There is one account of making a sublingually active DMT mix by mixing 1 gram of Virola calophylla resin with 60 mg of Calcium Hydroxide. The Calcium Hydroxide will burn a bit but not as much as pure DMT does. A pH of 9 is required to absorb everything better. 1g produced decent visuals and a light trip. An other suggestion is to use the Virola calophylla resin as a quid in the cheek. Mix about 1g of resin with 60 mg of Calcium Hydroxide and add a little water. Add just enough to make it sort of like clay. Roll it into a long capsule like shape and put it in your cheek. Slowly suck on it for 10-15 minutes. This traditional method is said to work very well, with no pain at all. 1g induces a moderate trip. Several grams a strong one. The advantages are that it it doesn't burn and the duration is longer than smoking DMT. the disadvantages are that big doses are hard to hold without saliva buildup /accidental swallowing and not everyone reports to experience sufficient intensity.

Safety

Sublingual DMT causes burning sensations and is not recommended.

6.2 Insufflating

Snorting DMT gets very opposite responses from different people. For most the pain hurts too much and is not worth the effects.

Preparation

There are reasons to believe that DMT-salts would be less caustic than DMT-freebase. It's reported that DMT Fumarate does not snort well. The effects are too weak. Some state, suggest, think that Fumarate should be less painful to snort than freebase. Others report to have tried it and find it just as painful.

Administration

Crunch the DMT to powder. Weigh the desired amount and lay it out in a line. Use rolled up paper to administer. Don't inhale too strong.

Snorting DMT can be combined with Harmalas. Administer the Harmalas orally and wait about a half hour before snorting the DMT. 40 mg Harmalas taken orally is reported to be sufficient. 20-30 mg Harmalas taken sublingually should work as well.

Although not commonly done Harmalas can be snorted. Harmalas is very active this way. 5-15mg per dose of DMT is sufficient. On the other side, Harmalas is active through other ROA aswell. Considering the possible health issues of snorting, its better to choose an other ROA.

Dosage

Snorting DMT without Harmalas:
Low: 50mg, medium 70mg, high: +100mg

Snorting DMT with Harmalas:
Low: 10mg, medium 20mg, high: +40mg

Effect

Snorting DMT lasts longer than smoking. The come-up is said to be more scary and less smooth. The onset takes approximately 5 mins. At 10 mins the plateau is reached. The peak lasts 30-45 mins. Snorting DMT combined with Harmalas prolongs the duration to around 2 hours and increases the effect - less DMT is better for your nasal passages.

Safety

It is unknown what possible health consequences snorting a basic alkaloid such as DMT can have on nasal passages. Especially long term use. There have been reports of bloody snot after snorting. Have a sterile saline solution to wash your nasal cavities afterwards. Although speculated, it is not known if snorting a salt form (DMT Fumarate) is less damaging than freebase. Snorting burns which is a sign from the body that somethings not going smoothly.

Snorting DMT causes burning sensations and is not recommended.

6.3 Nasahuasca

Nasahuasca is the dissolving of DMT-salt into a (preferably saline) solution which is sprayed or dropped into the noise.
The advantage is less irritation than snorting.

Preparation

Quote:
Hyperspace Fool's COCO Tek For Insufflation Of DMT:

1) Take your dose of DMT and place it in a small shotglass.
2) Mix with enough mildly hot water so that 1 drop will equal 20 mg spice (use more water if needed to dissolve everything).
3) Add a touch of vinegar to convert freebase to acetate (not needed with salt spice).
4) Add a few drops of COCONUT CREAM (not oil, not water)... until solution is cloudy and white.
5) Mix thoroughly and suck it up into an eyedropper.
6) Drop the drops into your nostril while inhaling to spread them over a larger surface of your nasal mucosa.

That's it folks. No burn, and a painless route into deep hyperspace. The end product should be like 10-15 mg per drop. Make it too watery and you will have too much drip. Using a nasal spray with a fine atomizing effect is nice, but not necessary, and for small amounts of solution, maybe impractical.

The longer duration than vaped spice makes this a rather attractive ROA.

NOTE: You can go ahead and add Harmalas to this tek if you want to potentiate the spice further... longer effect and less DMT required. Be warned that with enough Harmalas, insufflated spice can last a long time and be more like Aya than anything else. And, of course, using this technique when already up on orally administered Harmalas is fantastic.

2nd NOTE: Actual amounts and precise measurements have been avoided on purpose because this is a very flexible ROA. Given that some people only need 15mg to get effects and others require well over 100mg, and the fact that most people prefer slightly different ratios here... it makes no sense to be overly specific. Harmalas make a big difference in dosage as well. If you used vinegar, than you might want a bit more cream as well, for instance. Don't worry if it doesn't make sense to you at first. You really can't mess up with this. Just make sure you fully dissolve the spice, and cream to taste. If your drops wind up being only 5mg per drop... don't worry. The drip isn't really that bad, tbh, and you can always lean your head off of a mattress or couch to keep the solution in your nasal cavities for a while.

Some people still get nasal burn using the method above. Evaporating the acidic solution leaving behind only DMT-salt seem like a better way. Adding table salt to the solution is also good as nasal passages are a salty environment.

Procedure:
- Put DMT-freebase in a small shot glass
- Add a bit of [room temp] pre-boiled water (= disinfected) to the shot glass
- Create an acidic solution of choice (or use vinegar eg.)
- Add drops of the acidic solution untill all DMT dissolves - steering helps
- Apply heat /airflow to evaporate the solution in the shot glass
- Oily DMT-salt is left behind
- Add some table salt to [room temp] pre-boiled tap water (or buy nasal spray)
- Add the saline solution to the shot glass as per desired ration of DMT
- Add Harmalas (HCL form) if desired (can also be administered through another route)
- Add a pinch of Sodium Bicarbonate if desired
- Pour the solution into a nasal spray bottle / glass pipette

Notes:
Ideally the solution needs to be as close to neutral pH as possible to avoid any discomfort and max absorption but also as concentrated as possible to require the minimum amount of drops. Sodium Bicarbonate can be added to increase pH to neutral, but too much could freebase the DMT and/or cause irritation. DMT-acetate is the most soluble form of DMT, so the least amount of saline solution needs to be added to make it dissolve.

Administration

Pour the saline solution with the dissolved DMT-salt into an empty nasal spray bottle / glass pipette.
A spray might work better due to more surface area.
Administer into noise.

Dosage

Users report mild effects at 50mg DMT and intense sub-breakthrough effects at 100mg.
Accounts are limited so you will have to experiment.

Effect

Onset 5-10min. Effect 30-45min.

Safety

If it burns try adjusting pH, alter the salt contents or other ratio tweaks.
For experimental purposes only. Frequent usage is not advised.

6.4 IV

DMT can be injected, but it is not recommend - see below.

Preparation

If one is going to do it in spite of contrary recommendations, then: take care in making many purifying steps (several recrystallizations /washes). Make sure it has no solvent or other chemical traces in the final product (redissolving the recrystallized product in USP grade acetone or ethanol and re-evaporating, scrapping and letting it dry completely before converting to fumarates in a sterile solution, etc.).

Administration

Apply using a clean and unused syringe.

Dosage

Intravenous: moderate dose: 0.2mg/kg; very strong dose: 0.4mg/kg
Intramuscular: 1mg/kg
Subcutaneous: 60-100mg

For the first try, take at most 0.2mg/kg, preferably less. And VERY importantly, do NOT do it by yourself, have a sitter that is experienced with needles inject for you and be there to make sure you are physically safe.

Effect

The effect is comparable to a high dose of vaporized DMT.

Safety

Injecting DMT is not recommended mainly for two reasons:

1: The only official research done with DMT by Rick Strassmann used FDA-approved ultra pure DMT fumarate. The quality of home extraction products is questionable, one may have solvent traces and other impurities that could be uncomfortable, painful or downright dangerous to inject.

2: The onset of the effects are so quick that one might not be able to take out the needle in time and accidentally ripping their vein out while in hyperspace, or putting it down too near and rolling around/puncturing oneself

Please consider why you would choose the IV route over other ROA, which are just as effective, like vaping.

6.5 Intrarectal

In the name of completeness the ROA section will be closed off with a route that doesn't come to mind quickly, but does exist:
inserting DMT anally. (Anahuasca?) Try at your own risk...

Preparation

Don't use freebase, convert into DMT-salt eg. DMT Fumarate. Use pre-boiled water (preferably distilled). Dissolving into vinegar, orange or lemon juice should work too. Add baking soda to reduce the acidity.

Administration

Cocoa butter is a good vehicle for introducing substances intrarectally. The melting point is below your internal temperature, but above room temperature. This makes it easy to handle because it's solid prior to administration, but it rapidly melts once administered. Or make a 2-5 ml solution and insert rectally via a needless syringe.

Dosage

Harmalas: 1/3 to 1/2 of an oral dose
DMT-salts: start with 100mg, add 50-100mg, 250-300mg is considered very high
Brews: 3g Mimosa + 3g Syrian Rue. Note: +10 ml liquid might be hard to keep in

Effect

Rectal administered DMT bypasses the first-pass metabolism and liver. Administration without Harmalas will have effect. But the intestines also contain MAO. Rectal DMT is therefor 3x less active when taken without Harmalas. Most users report that the DMT is less potent than orally. The effect of Harmalas is 3x more potent than orally.

Effects start at about 20 minutes with a powerful initial body load, the peak lasts 1 hour with an afterglow of several hours. The pharmacodynamics of intrarectal vs. intranasal administration seem to be very similar. There are no unique effects compared to other methods. It is reported that the anal route does not burn or hurt. It also eliminates nausea due to stomach irritation. However it can still give a bloated feeling. And it's possible to get nausea just from the vertigo of high amounts of tryptamines or RIMA.

Safety

The pH of a brew should not be detrimental to tissues. However, a large dosage of acidic Mimosa brews may not be good. Adding baking soda reduces the acidity. Note that substances inserted rectally don't get filtered by the liver. They go right in to the bloodstream. Taking things anally is closer to injecting than swallowing. Being less active than orally and oral purging being considered medicinal, this route makes little sense.

Please consider why you would choose the anal route over other ROA, which are just as effective, like oral.

6.6 Safety - other routes of administration

When using these other routes always make sure that the alkaloids are as pure as possible and of good quality. IV is the least safe due to injecting possible impurities straight into the blood stream. This is the least advisable route and should definitive be avoided. Taking things rectally is closer to injecting than swallowing as rectal administration bypasses the liver. Snorting and using sublingual DMT causes irritation. This is a sign from the body that somethings not going smoothly.

As can be seen, most of these routes have potential safety issues and are not recommended.

7. Additional info

7.1 Making Changa

From 10x Caapi leaf

Step 1 - boost some Caapi leaf
Option A) boiling in water:
- place 9g of Caapi leaf (or powdered vine) in a pot and add water
- bring to a slow boil or simmer for a couple hours adding water to keep the level consistent (or do multiple boils)
- filter and discard the plant material
- simmer the volume of the liquid down to a low level
- add a fresh gram of Caapi leaf (or other herb if you can't find) to the reduced liquid
- simmer the liquid into the leaf, evaporate the last bit of moisture dry
> now you have 10x Caapi leaf

Option B) soaking in alcohol:
- place 9g of Caapi leaf (or powdered vine) in a jar
- add 96% alcohol or IPA and close the lid
- let it soak for +2 weeks (1 month)
- filter and discard the plant material
- place the jar with the solution in a warm water bath (double boiler), use an electric heater, no open flame
- simmer the volume of the liquid down to a low level
- add a fresh gram of Caapi leaf (or other herb if you can't find) to the reduced liquid
- simmer the liquid into the leaf, evaporate the last bit of moisture dry
> now you have 10x Caapi leaf

Step 2 - add other herbs
- add the 10x Caapi leaf to a blend of herbs chopped to a good consistency for smoking
- if desired boost some of the other herbs as explained above
- a herbal blend example is: 50% 10x Caapi + 25% 10x Blue Lotus + 25% Mullein
> now you have the herbal base for Changa (note: this can also be smoked separately if DMT is vaped pure)

Step 3 - infuse with DMT (Warm Water Bath Tek)
- weigh the amount of herbs and DMT you want to combine
- a common ratio is 1:1 (1 unit of DMT to 1 unit of herbs) down to 1:3 DMT/herbs
- put the herbs in a shot glass and carefully spread the DMT evenly on top of the herbs
- place the shot glass in a bowl of boiled water. Don't get the inside of the shotglass wet
- the hot water outside will heat the shot glass and melt the DMT into the herbs
- covering the bowl with a towel creates steam which helps to melt the DMT faster
- repeat with additional sessions of boiled water if needed
- remove the shot glass from the bowl when the DMT has completely melted into the herbs
- mix well and let it cool down
- see: "Warm Water Bath Tek" for more info and pics
> now you have Changa

Note: DMT can also be dissolved in 96% Alcohol, IPA or Acetone. Add the DMT solution to a blend of herbs and allow it to evaporate.
This will take much longer to dry than the 'Warm Water Bath Tek' explained above.

From Harmala alkaloid extract

Step 1 - obtain Harmala Alkaloid extract
Option 1) From boiled down powder
- reduce Caapi leaf solution (as explained above) without adding any new leaf
- evaporate the remainder of the liquid and scrape up the powdery residue
Option 2) From a proper extraction
- refer to the Nexus Wiki for various Caapi /Rue extraction teks
Option 3) From an online shop
- various sites sell it (search)

Step 2 - infuse with DMT
- dissolve the Harmalas into a solvent and add DMT (use about 40ml solvent per gram of DMT)
- alcohol or an other form of ethanol can be used as the solvent. Eg: 96% Alcohol, IPA or Acetone
- a common ratio is 1:3 Harmalas/DMT up to 1:1 Harmalas/DMT
- add the solution to a blend of herbs on a dish (usually 1:1 DMT/herbs)
- spread the herbs out evenly, about 5-10 mm high
- if needed, add some more solvent so all leaf is well covered

Step 3 - evaporate dry
- once everything is soaked up, fluff it up and let all traces of solvent evaporate
- place the dish somewhere where it will stay undisturbed for several days
- it can take four days for Acetone to completely evaporate and the leaf to dry
- once dry, the leaf can be weighed. It should be heavier by the amount of alkaloids that it was enhanced with
> now you have Changa

7.2 About dabbing

Terminology

Rig:
Can be an ordinary bong (water pipe). Custom bongs sold as dabbing rigs exist (usually with male joint).

Joint:
Part of the bong. Outer glas extension sticking out of the bongs body. The joint holds the nail. It can either be male or female. A male joint fits inside a nail, a female joint goes over it. There are 3 universal sizes: 10mm, 14mm, and 18mm. Male joints are better for dabbing. The glass can't break if a hot nail expands.

Percolator:
Part of the bong. Inner glass extension of the joint, reaching under water. Has holes for air flow. The number and size of the holes influences the air flow (pull force) and bubble size (temperature drop). There are various types of percs with specific air flow properties.

Nail:
The actual dabbing unit which gets heated and holds the extract. The nail is connected to the joint. Nails can be made from glass, quartz, titanium and ceramic. There are domed and domeless nails.

Domed nail:
A nail combined with a dome. A domed nail has no holes on top where the oil is. Airflow travels over it, to underneath into a pipe. A glass dome surrounding the nail is placed over it after the nail is heated and dabbed.

Dome:
The glass part that is placed over a domed nail. The dome holds the vapor inside. It has a small opening at the top. The opening helps to capture and direct the vapor back down through the pipe when it comes off the nail.

Domeless nail:
Open nail without dome mechanism. Has holes on top where the oil is. When inhaling air through the holes, the vapor is sucked in. If the nail cools too much, vapor can escape into the air.

Carb cap:
An external cover for a domeless nail. Has holes for air intake. Doesn't let vapor escape in the air, constricts airflow, holds in heat. Usually put on the nail at the last stage when the nail cools. Can be use for low temp dabbing on if the nail is heated less and covered directly. Created the same advantage a domed nail has.

Banger:
A banger is a type of domeless nail. Instead of having an open roof with holes round a circle, it's shaped like a small shotglass with a hole at the side.

e-nail:
Nails with electric heating. Can also be a normal nail that fits in a separate electric coil with temperature control. Eliminates the need to use a torch. Can be used to accurately set different vaporization points for different materials.

Dabber:
The rod used to apply the extract to the nail. Shaped as a long thin screwdriver.

Seasoning:
The removing of unwanted polish and coating materials from new nails. Must be done prior first use. The nail is heated and oil is applied. Usually Cannabis oil is used. DMT can be used as well. Nothing is inhaled. Seasoning improves vaping efficiency and taste.

Domed nails vs domeless nails vs e-nails comparison

Domed nails:
+ helps to hold in vapor
+ protection from hot nail
+ heats up quickly
+ cheaper
- dome must be slid in place, additional action
- dome can break, more fragile
- harder to place spice on
- cools down quicker, less time for functional use
- less air flow, less efficient for DMT

Domeless nails:
+ easier to place spice on
+ takes longer to cool down, more time for functional use
+ more airflow, better for DMT
+ carb cap holds in heat and vapor
- longer to heat up
- no protection from hot nail, more dangerious
- more expensive

e-nails:
+ eliminates the need to use a torch
+ precise and constant temperature control
- much more expensive

Use a domeless nail (banger).

Nail material comparison

Glass: breaks very easily and doesn't last long. Retains the least amount of heat.
Ceramic: more prone to breaking; retains heat the longest; reported to have worse /harsher taste compared to Quartz.

Don't use glass or Ceramic.

Quarts vs Titanium:

Quartz:
+ cheaper
+ much better flavor, less harsh hits
+ impossible to overheat
- takes longer to heat up
- retain less heat, less time for functional use
- shorter lifespan and more prone to breaking

Titanium:
+ virtually indestructible - impossible to crack
+ heats up quicker
+ retain heat longer
- must be re-seasoned after several uses with spice
- risk of overheating and burning the extract
- worse taste
- more expensive
- health risks from inhaling hot metal vapor (Titanium dioxide is a possibly carcinogen)

Use Quartz.

Seasoning

Some say Titanium can be seasoned by heating with a torch then cooling with cold water. Others say this is not good and that it's best to season it with what you will use it for. Quartz also need to be seasoned. Do some lower temperature DMT dabs until it gets gray and opaque. Some mention seasoning with Coconut oil, but insufficient information is available.

Torch fuel comparison

Propane:
+ very cheap
+ larger tanks and more efficient: lasts longer
- will damage some nails over time, especially Quartz

Butane:
+ no damage to nail
- smaller tanks and less efficient: more refueling
- expensive

For Quartz use Butane.

Note: a large torch is needed to light the nail. An Arc Turboflame sized ligher is too small.

7.3 e-Cigarette info

An e-cigarette is a device that converts electrical energy into heat to vaporize a viscous liquid composed of vegetable glycerine and/or propylene glycol (e-juice). Every e-cigarette has at least three main components: a power source, a tank and an atomizer. The atomizer sits in a tank filled with e-juice and exists of a coil surrounded by a liquid absorbing material called a wick. The coil is electrically heated by a power source, heating the e-juice turning it into vapor. The wick regulates the flow of e-juice to the coil. This produces the right amount of vapor at a reasonable rate.

Types of e-cigarettes

Dripping Atomizers
The atomizer coil is located on the bottom with a metal mesh or silica wick on top. Dripping Atmomizers have a fairly small capacity and are best for people who prefer dripping. Users drip small amounts of e-juice directly on to the coils and wick before every few puffs. Dripping Atomizers are complex, inconvenient and needs to be continuously refilled. Rebuildable atomizers (power increase) require considerable skill. Its hard to track amount of e-juice left inside. All this makes them not suitable for what we need.

Cartomizers
Cartomizers have their artomizers housed inside a cylindrical tank. This allows a cartomizer to hold a lot more liquid than a dripping atomizer. The coil is surrounded by Polyfill which functions as the wick. It absorbs e-juice allowing for a longer vape time. The main disadvantage of cartomizers is that they are not suitable for heavy vaping - which we need.

Clearomizers
Clearmizers are the newest devices on the market. They differ from cartomizers by having transparent tanks. This lets you see how much e-juice remains. Instead of polyfill they have a wick made from a fibrous material, usually organic cotton. This allows for heavy vaping. Some designs feature top coils with longer wicks. Others have bottom coils with short wicks. Bottom coils produce cooler vapor, have better wick saturation and allow for lower e-juice levels.

+ prefabricated, no need for manual building
+ large capacity of e-juice for sufficient vapes
+ transparent tank allows you to see exact amount of e-juice left
+ atomizer heads are easy to snap on and off and cheap to replace
+ allow for easy customization if desired (different Mod Boxes, OCC, RBA)

The development of sub-ohm vaping

Sub-ohm vaping is vaping on a device whose atomizer coils have a resistance of less than one ohm. This increases the power output to create more vapor. When vaping using sub-ohm coils a substantial amount of vapor is produced compared to using coils above 1 ohm on the same device. This is because sub-ohm vaping utilizes the principles of Ohm's and Joule’s laws of electricity: a non-variable voltage source (battery) in a mechanical vape mod will increase the overall power output (wattage) of your device when you decrease the resistance (ohms) of your coils. As you decrease your resistance you will increase the amperage your device uses to supply the current needed. Up to recently, sub-ohm vapes were not sold so you had to build one yourself.

Rebuildable Dripping Atomizers (RDA)
Rebuildable drippers are the original way to sub-ohm. They are small devices that attach to Mechanical or Box Mods. They contain a deck where coils are built wicked with cotton attached using a screwdriver. Rebuilding requires considerable skill.

Rebuildable Tank Atomizers (RTA)
For people who want to build coils but do not want to drip. RTA’s are essentially clearomizers that require the user to build their own custom atomizer (sub-ohm coil and wick). Rebuilding requires considerable skill.

Sub-ohm Tank Clearomizers
Similar to RTA’s except that Clearomizers can be bought 'sub-ohm ready'. This means you don't need to build anything yourself anymore. The internal atomizers come in the form of pre-made disposable coil+wick packs called OCC's (Organic Cotton Coils). OCC's are easily swappable when due for replacement. Instead of OCC's you can also buy RBA's (ReBuildable Atomizers) The wick of a RBA can be easily manually changed when due for replacement while the coil is left inside. RBA's are cheaper to maintain than OCC's and are said to vape better.

As can be seen, if you wanted to sub-ohm in the past it would require considerable skill. These days all it takes is the purchase of a sub-ohm Clearomizer with OCC /RBA and a Box Mod with sufficient Watts. This setup makes it possible to inhale a large amount of e-juice with sufficient DMT in a single puff. A couple of years ago with the pen-type vapes this was not possible.

What you need

Mod Box
For DMT 40-60 W is sufficient. A 100W box able to power a 0.5 ohm coil gives plenty of over-capacity for vaping at around 50W. The batteries will run cooler than a 50W box. Look for a Mod Box with a large range eg. 10W-100W. This enables you to find your preferred spot. A good Mod Box displays voltage, watts and coil resistance. Some Mod Boxes support both variable Wattage and temperature control. Certain metals increase in resistance when the temperature goes up. By applying power and measuring to reach a known resistance at a certain temperature, a mod box can reach and stay at that temperature. Note that some coils are 0.15 ohms. When using these, make sure your mod box and batteries can handle it!

Batteries
For sub-ohm vaping your batteries are the most crucial component of the setup. Only a few lithium battery types are suitable. Batteries can either be high storage capacity (mAh) or high drain capacity (Amps). High storage requires less charging. High drain gives more current. Sub-ohm coils should only be used with high-drain batteries. ICR (LiCoO2 or LiCd) batteries are usually rated for their higher storage capacity (mAh). They are often unable to safely deliver the amperage needed for high power, low resistance devices. Being high risk, ICR's are commonly sold with protection circuits. IMR (LiMn) batteries allow higher drain rates compared to ICR's. This makes them much more suitable for low resistance devices. IMR batteries use safer chemistry than ICR's and don't have a protection circuit built in. Note that they should never be discharged below 2.5 volts or cycle life/performance will be reduced. Packing your Mod Box with 3.7V, 30A MCD, 18650 type, IMR batteries from a well-established manufacturer ensures you have the best you can get, so you can't go wrong.

Clearomizer
A relatively small Tank is preferred: 1.5 - 2ml. Allows for experimentation with spice concentrations. Also saves on making large amounts of spice to mix in. 2ml should be good for 10+ hits. Buy a tank that can be refilled from the top, this is convenient. Also, make sure the tank isn't prone to leakage. The 'Kangertech CL tank 2.0' is said to be good.

Coils
Coils come manufactured in OCC's or RBA's. Your Clearomizer will come with them included. When buying new ones make sure they are compatible with your Clearomizer. Coils can be made of different metals such as Stainless Steel, Nickel, Nichrome, Titanium and Kanthal. Some can be used for temperature control mode (Ni, Ti), some for wattage control (NiCr, Kantal) and some for both (SS). Nickel and Titanium can release hazardous chemicals when heated over a certain temperature, that's why they should only be used for temp control. Note that no one talks about this danger for titanium dabbing nails.

e-Juice
PG (Propylene Glycol) and VG (Vegetable Glycerin) are odorless liquids that are combined with flavor to create e-juice. They produce vapor when heated, which allow them to be inhaled. PG is a petroleum by-product. The fluid has no odor or color, and is less viscous than VG. In vaping it is used to provide a ‘throat hit’. Some users claim is similar to the sensation experienced when smoking tobacco. It also carries flavor more effectively than VG. VG is a natural chemical derived from vegetable oil. The hit from a high VG fluid is a lot smoother than with PG, making it more suitable for sub-ohm vaping. The increased thickness of VG means it can reduce the life of Atomizers quicker than PG-based juice. High ratio VG liquids clog up coils more rapidly and will not work well in certain tanks. A good ratio is 50/50. Note that some studies suggest that e-juice flavors are toxic when smoked. For DMT buy zero-nicotine 100% pure flavorless VG and PG and mix them to your desired ratio preference (50/50 - 40/60 PG/VG).

Clearomizer kit components (for reference only)

- Batteries: The power source of the device. Located inside the Box Mod.
- Box Mod: The unit which controls the power output and holds the batteries.
- Tank: Holds the e-liquid and Atomizer. Sits on top of the Base.
- Base: The bottom part of the Tank. Screwed into the Mod Box. Usually has airflow control.
- Atomizer head: Either OCC or RBA (see below). Located inside the Tank.
- OCC: Organic Cotton Coils contain the coil and wick. They come pre-built and get replaced when used up.
- RBA: ReBuildable Atomizers are designed to be refurbished with new wick when used up.
- BTC: Bottom Turbine Coil is prefered over top coil.
- BTDC: Bottom Turbine Dual Coil has two coils for cooler vapor. More batteries, more Watts, shorter battery life.
- Wick: Usually made from organic cotton. It either fills the empty space inside the coil or is wrapped around the outside.
- Coil: Wire from a metalic alloy. Comes pre-made with the resistance desired.
- e-juice: Stored in the Tank.
- Drip tip: Tube on top of the Tank from which you inhale.

7.4 DMT Extraction

Safety

- never handle flammable solvents near open flame or fire, use warm water baths on electric stoves
- always use solvents in a well ventilated place only
- use stainless steel or glass hardware, no plastic or aluminum
- wear gloves and eye protection when handling corrosive substances
- search for product msds (contents), see FAQ wiki for more info /links
- check that solvents evaporate clean
- purify final yield by taking additional clean up steps

Don't worry: you won't burn your fingers a-la fight club from the lye solution at the dilutions used, get brain damage from inhaling a bit of petroleum fume, or intoxicate yourself from consuming a less than pure yield. Use some common sense caution though.

Products

The following products can be chosen for various extraction /purification procedures. As can be seen, DMT can be extracted with food safe /household products. When ordering chemicals, preferably use cash when buying them in a store, or Tor /VPN when ordering online.

Acids
- Acetic Acid (Vinegar) - household product, food safe
- Citric Acid (Lemon Juice) - food safe
- Phosphoric Acid - food safe
- Fumaric acid - dietary supplement, food safe
- Hydrochloric Acid (HCl, Muriatic Acid) - toxic

Salts
- Sodium chloride 'NaCl' (Table Salt) - food safe, should not have any additives
- Magnesium Sulfate (Epson salt) - food safe

Bases
- Sodium Hydroxide 'NaO' (lye) - high pH danger, suspicious to order (known for meth production)
- Potassium Hydroxide 'KOH' - high pH danger
- Calcium Hydroxide 'Ca(OH)2' (lime) - safer pH, food safe
- Sodium Carbonate 'Na2CO3' (washing soda) - safer pH, household product, food safe
- Sodium Bicarbonate 'NaHCO3' (baking soda) - food safe, should be changed to sodium carbonate

Polar protic
- Water - can be tap water, but preferably distilled or de-mineralized

Polar aprotic
- Acetone '(CH3)2CO' - low toxicity, food additive, suspicious to order (known for meth production)

Alcohols
- Ethanol 'EtOH' (Alcohol) - food safe, usually 96% pure (4% water)
- Methanol 'MeOH' - toxic
- Isopropyl Alcohol (IPA, Rubbing Alcohol) - should be >99% pure, less toxic than methanol
- Butanone (MEK) - irritant

Non Polar
- Naptha (petroleum) - freeze-precipitates, various petroleum derivatives, toxic, suspicious (known for DMT extraction)
- Octane (petrol) - freeze-precipitates, not usually used (don't use), very explosive, toxic
- Nonane (kerosene) - freeze-precipitates, not usually used (don't use), toxic
- Heptane /Hexane (aliphatic) - evaporates, pulls a narrow alkaloid spectrum, higher temp needed, can be used for re-x, toxic
- Methylene chloride (DCM) - evaporates, pulls full spectrum, efficient at lower pH, requires clean-ups, suspicious, toxic
- Xylene /Toluene (aromatic, paint thinners) - evaporates, FASX, pulls full spectrum, toxic
- d-Limonene (citrus oil) - evaporates, FASX, pulls full spectrum, low toxicity, food safe
- Limonene - distilled d-Limonene - purer product, same as above
- Cooking oil (sun flower, olive, etc) back salt or FASI/W, more prone to emulsions, food safe

Grades: Food grade has high purity and undergoes food-safe processing. Lab grade has high purity, yet can be processed in unclean containers with residues of other chemicals. Lab grade can therefore can be toxic even though the product is food safe itself. Technical grade is of low purity and can contain miscellaneous chemicals. Preferably choose food grade, however this can be hard to find. Avoid tech grade, this can ruin the extraction or contaminate the final yield.

Safety: Always work with solvents in a well ventilated place. Especially with hydrocarbons. There are scientific studies which conclude that d-Limonene fumes can be carcinogenic as they react with ozone in the air to form formaldehyde, concluding it's safer not to buy d-Limonene scented candles and cleaning products.


A/B (Acid/Base)

The DMT alkaloid is found in the form of DMT-salts in plants. Acidification (< 4 pH) helps to release the active alkaloids from the plants into the water. Basing (> 11 pH) converts the salt form of DMT into DMT-freebase. A non polar solvent (NPS) is added (eg. Natha) to "pull" (move) the freebase DMT from the basic solution into the NPS floating on top of the basic solution. The NPS is separated and evaporated dry leaving freebase DMT behind (or frozen lowering the saturation). Note that only freebase DMT can move to a NPS solution, DMT-salt will not. This is convenient as freebase is what we need for smoking.

Quote:
Step 1 - acidify
Add water with < 4 pH (eg. vinegar) to the bark. Acidification helps to release the actives from the bark into the water. At this point the DMT is in its natural salt state.

Step 2 - salt (optional)
Adding salt saturates the solution pushing more actives out into the solvent. It also reduces the chance of emulsions.

Step 3 - base
Increase the solution to > 11 pH (using lye = sodium hydroxide). The high pH will convert DMT-salt to DMT-freebase. This is an instant reaction. When it happens the solution changes color to black.

Step 4 - pull
Adding a non polar solvent (NPS) pulls the DMT from the basified solution into the NPS. The NPS does not mix with water - it floats. The DMT containing NPS solution is separated. This is repeated several times. The basified solution depleted of actives gets discarded.

Step 5 - wash (optional)
A sodium carbonate wash will clean the NPS from any remaining lye and other impurities. A mini A/B will purify the NPS from precipitating plant oils and organic substances, making the DMT whiter.

Step 6 - evaporate
Some NP solvents are evaporated to leave behind DMT. Others such as Naptha can be frozen to precipitate the DMT out. With freeze/precipitation the solvent can be washed and re-used.

Step 7 - clean-up (optional)
Use an additional clean-up step to purify the final yield.

pH level
Don't worry about exact pH levels. For the acidic part the alkaloids are already in salt form in the plant. The plant is acidic so it will already be water soluble. The acid just helps break down the plant material. It also guarantees the solution is acidic in case your tap water is very basic. For the basing part, add lye until the solution goes totally black and more to avoid emulsion complications.

Temperature
Extracting DMT isn't cooking Ayahuasca. There is no need for near boiling temps. Acidifying: < 60 deg C, basing: < 50 deg C, pulling < 40 deg C. Too much heat will pull plant oils into the NPS resulting in a less pure (more yellow and sticky) product. Naptha pulls at room temp give clean spice and eliminate the need to a clean-up. They do give a slightly smaller initial yield, but not much less compared to re-x'ing yellow spice from warm pulls. Heptane and Hexane need higher pulling temps (> 40 deg C).

Times
Acidify for 2 hours (or more). Basify for 1 hour (or more). More time could benefit eg. leave for a day at room temp. When pulling, gently roll the bottle for 30-60 seconds, let the layers separate, repeat. Freeze the Naptha for 12-18 hrs or more. Dry final yield for a day (or more) to make sure all NPS evaporates.

Emulsions
If an emulsion forms during the pulling stage sprinkle with plenty of salt. If that doesn't work add more lye. Heating helps too. Another option is vibrating the emulsion loose. Note that the first pull can occasionally take up to an hour to separate.

Salting
Salting saturates the solution pushing the actives into the NP solvent more efficiently. This helps avoid emulsions, increases yield and reduces the amount of pulls required. Cyb's ATB Tek states 30g, but you may add 30g more (60g in 200ml water). This further reduces the risk of emulsions.

Number of pulls
Most teks advise 4-5x 50ml NPS pulls. However salting can result in >90% yield in the first two pulls. The larger the volume of NPS, the more it can hold. You could say 3x 60ml pulls should get most actives out.

Naptha saturation
It is a misconception that less saturated naptha precipitates out less DMT. The higher the saturation, the faster the crystallization. Also, the colder the temperature, the faster the crystallization. The faster the crystallization, the quicker the crystals fall out and the smaller and more abundant they are. More saturated colder naptha yields smaller crystals faster. Less saturated less cold naptha yields larger crystals slower. In the end the final yield is the same. Evaporating naptha prior freezing is not strictly necessary. Freezing several days longer requires less effort and is less of a waste. It takes a very low saturation to not precipitate out any DMT.

Separation
Do not disturb the dish before 24 hours are up, the crystals may not form properly otherwise. When separating the DMT from the frozen Naphta don't use coffee filters. Some DMT might dissolve into them. Decant the cold Naphta. If the DMT sticks to the glass, place the container upside down on a plate in the freezer. Let the naptha drip down, then take out of the freezer and evaporate dry.

Scaling
Don't over-complicate on exact ratios. To acidify, add sufficient water to submerge all the bark and add a bit of acid. Base until all goes black, then add some more. Make sure there is enough water to work with the bottle. The Nexus DMT FAQ wiki states that per 1g bark: 15ml total water volume, 1g lye and 0.5mg NPS can be used. However, more optimized ratio's are:

7ml (up to 10ml) water volume : 1g bark
0.5g (up to 1g) lye : 1g bark
0.5ml NPS : 1g bark

To extract 100g bark, 700ml total water volume, 50g lye and 50ml NPS pulls can be used. These same amounts can also be used to extract down to 50g. Adding relatively more water to bark ratio helps to fill the bottle, adding relatively more lye decreases the change of an emulsion and more naptha aids in pulling. However, you can also extract 50g bark with 350 ml total water volume, 25g Lye and 25ml NPS pulls. To extract 300g of bark split it in 3 separate containers with 100g each.

Warning: it is not advisable to do large scale extractions (safety /law). The Nexus is pro small extractions for personal use only. Please keep it safe, don't ruin it for the rest.

Dark solvent
After mixing the solvent with the basified MHRB solution, sometimes the separated naphtha layer becomes very dark brown. It seems to happen mostly with STB extractions, powdered bark and heated pulls. The exact reason is unknown. Wait a few hours and see if the color settles and the solvent layer gets clearer. If that doesn't help separate the pulls as you would normally and do a sodium carbonate wash. If this isn't sufficient do a mini A/B.

Cleaning
If you want to eliminate any possible lye or other polar impurities from the NPS, you can do a sodium carbonate wash:

Quote:
Step 1 - the product is dissolved in a NPS (naphtha/heptane/hexane)
Step 2 - add 5-10 grams of sodium carbonate to 100 ml of water (basic solution)
Step 3 - mix the two solutions above and shake well (emulsions will not form)
Step 4- separate the NPS from the basic solution and discard the basic solution

If you want to remove plant oils and organic substances for whiter DMT from MHRB do a Mini AB:

Quote:
Step 1 - combine all NPS pulls together (or dissolve impure dmt into a NPS)
Step 2 - create an acidic solution and add the NPS to it
Step 3 - wait 10-15 minutes for all the dmt to travel to the acidic solution
Step 4 - separate and discard the yellow NPS
Step 5 - basifiy the solution and pull with fresh NPS
Step 6 - clean the NPS from any remaining lye with a sodium carbonate wash (optional)
Step 7 - freeze, decant, dry

To clean up dirty DMT you can do a re-x (re-crystallization):

Quote:
Step 1 - add 1g of DMT to 40-50ml of hot naptha (warm water bath)
Step 2 - add the DMT, let the naphta cool down for a couple of minutes
Step 3 - observe impurities precipitate out
Step 4 - discard the impurities and freeze/precipitate the naptha

An other way to clean up dirty /impure freebase DMT obtained from an A/B tek is to a FASA wash:

Quote:
Step 1 - create anhydrous acetone, see "Making anhydrous solvents" under FASX below
Step 2 - convert the DMT into DMT-Fumarate, see "Converting DMT-Freebase into DMT-Fumarate" under FASX
Step 3 - (optional) clean the DMT-Fumerates, see "cleaning" under FASX below
Step 4 - convert back to freebase DMT, see "Converting DMT-Fumerate into DMT-Freebase" under FASX

Some teks tell you to do a defat (wash) after the acidification stage. This means adding Naptha to the acidified solution to extract impurities into the Naphta which is discarded. This step is now considered outdated as its inefficient at cleaning and wasteful in terms of time, Naphta and yield loss. Another cleanup not advised is washing the NPS with charcoal, this can easily result in yield loss.

A/B Teks
- For MHRB use: Cybs Hybrid ATB SaltTek (If it's your first time extracting, start with this tek)
- For ACRB use: Earthwalkers ACRB TEK 100g "PICS" (Newbie Friendly)


STB (Straight To Base)

The STB path is similar to A/B. The only difference is that the acidification step is left out.

Quote:
Step 1 - base with high pH
Step 2 - pull with NPS
Step 3 - separate (evaporate /freeze /salt out)

People new to extracting sometimes think STB is easier than AB because it skips a step. In reality the acidification step is really simple: just add acid prior adding base. All you need is vinegar, obtainable in all grocery shops. Not using acid means extending the basing step to make sure all DMT leaves the bark and gets converted to DMT-freebase. This makes the process longer.
MHRB can be done by STB, ACRB (more fat-laden) needs to be done by AB.

Having said that, STB is an option when pulling "dry" with more polar solvents like ethanol, see endlessness's eco tek for more info.
Note that dry teks with the usual NP solvents, a lot of solvent can get soaked (trapped) in the bark.

STB Teks
- Lazyman's tek
- Noman's tek
- Dream Weaver's tek


FASX (Fumeric Acid Saturated Acetone /IPA /Water)

DMT Salts
When freebase DMT is added to an acid it changes to a DMT salt. DMT-citrate is created by adding citric acid, DMT-Fumerate is created by adding Fumaric acid, etc. The advantage of DMT salts is that they are very stable, good for long term storage. Freebase is only used for smoking. Salts are used for all the other routes such as oral (pharmahuasca). Most DMT salts are hygroscopic. This means they absorb water from the air which makes them permanently moist (a goo). DMT-Fumerate is the only salt that isn't hygroscopic. It crystallizes which makes it much easier to handle. All DMT salts can easily be converted to freebase if required for smoking. As well as the other way around.

FASA
FASA stands for Fumeric Acid Saturated Acetone. It's created by adding Fumeric Acid (FA) to Acetone until the Acetone is saturated (SA). The methodology of FASA employs the solubility of freebase DMT, the solubility of Fumaric acid and the insolubility of DMT-Fumarate in Acetone or non-polar solvents utilized for extraction. When FASA is added to a solvent in which freebase DMT is dissolved, the FA salts the freebase DMT into DMT-Fumerate. DMT-Fumerate is not soluble in the solvent and precipitates. As it's the only thing that does, it can easily be separated. This means that solvents such as d-Limonene which pull full-spectrum don't need to be evaporated anymore. They can be cleaned and re-used. A big advantage in terms of efficiency and sustainability.

Solvents
Acetone, d-Limonene (limo), Xylene and Toluene are reported to work well. Xylene, Toluene and d-Limonene pull a full spectrum extract (red jungle spice) from MHRB. Acetone pulls less jungle alkaloids. Acetone is a normal part of human metabolism and is present in fruits in small amounts. D-Limonene (citrus oil) is sold as a dietary supplement, not suspicious to order and smells like oranges (fumes aren't healthy, ventilate). Test your solvent: add some FASA to a clean batch of solvent slowly drop wise to see if anything precipitates out. If the solvent stays clear, it's good. Next, dissolve some (25mg) of DMT in an other batch of solvent. It should dissolve. Now, add the FASA and DMT solvents together. If clouding forms (DMT-Fumerate precipitation) the solvent is good to use. Naptha does not work as FA precipitates out. If FA precipitates out of your d-Limonene, try adding some Acetone to your Limo (25ml Acetone per 100ml Limo) prior adding the FASA.

Procedure

Quote:
Step 1 - follow a tek (of choice) to pull DMT into a solvent which works for this method (Xylene /Toluene /d-Limonene)
Step 2 - saturate acetone with Fumaric acid (FASA)
Step 3 - add the FASA drop wise to the DMT saturated solvent
Step 4 - keep adding until cloud forming stops, add some more for good measure
Step 5 - wait 24 hrs to allow the DMT-Fumarate to crash out
Step 6 - filter the DMT-Fumerate crystals out
Step 7 - wash the DMT-Fumerate with a fresh batch of acetone to dissolve any excess NPS and FA
Step 8 - filter the DMT-Fumerate out and dry
Step 9 - clean the NPS for re-use by adding water, excess FA and aceton will dissolve into the seperate layer of water
Step 10 - convert to DMT-freebase if desired

FASA vs FASI / FASW / CASA
Other than FASA (Acetone), also FASI (IPA) or FASW (water) can be used on various NPS solvents. With FASW a separate layer of water forms under the NPS in which the DMT-Fumerate is dissolved. First the NPS is separated then the water is evaporated dry. With FASI a separate layer of IPA forms under the NPS in which the DMT-Fumerate crystallizes out (not soluble in IPA). First the NPS is separated then the DMT-Fumerate is filtered from the IPA. CASA stands for citric acid saturated acetone. CASA eliminates the need for a basing stage. See the Tek: "The FASA Method". When CASA + FASA is used, DMT-Fumerate precipitates in the acetone. Some people report an oily orange layer form on the bottom with this tek. Might be due to their acetone not being anhydrous enough. Dehydrating the bark might help too.

Note: instead of using FA, other acids (vinegar, citric acid, etc) can be used to saturate water added to the NPS. However, when the bottom layer is evaporated, the DMT salt will be a difficult to handle hygroscopic goo. Hence FA is preferred.

FA saturation and ratio to DMT
1/3 part Fumaric acid to 1 part DMT-freebase (in weight) should convert all DMT-freebase to DMT-Fumerate. Using excess FA is not a problem. In fact it's safer to get all the DMT out and can easily be cleaned afterwards. A ratio of 1/2 FA to 1 DMT is more than plenty. 100g bark with 2% DMT contains 2000mg DMT, so 1000mg FA needs to be used. This dissolves in:
- IPA saturates @ 5mg/ml with FA. Use around 200 ml FASI saturated with ~1000mg FA per 100g bark.
- Acetone and water saturate @ 6mg/ml with FA. Use around 170 ml FASA/W saturated with ~1000mg FA per 100g bark.

Cleaning
Cleaning excess Fumaric Acid from final yield (Note that Fumaric acid is a dietary supplement):

Quote:
Step 1 - add a fresh batch of Acetone (or NPS) to the DMT-Fumerate
Step 2 - excess FA will dissolve in the solvent, DMT-Fumerate will not
Step 3 - filter and dry the DMT-Fumarate
Step 4 - clean the solvent with water for re-use

Cleaning excess d-Limonene from final yield (Note that d-Limonene is a dietary supplement):

Quote:
Step 1 - obtain anhydrous IPA, or make anhydrous with Epson salts (see below)
Step 2 - dissolve 1000 mg of DMT-Fumarate in 30 ml boiling hot IPA (water bath)
Step 3 - quickly filter with cotton (especially if undissolved solids are observed)
Step 4 - put the hot IPA in the freezer right away and leave for 1-2 days
Step 5 - filter the precipitated DMT-Fumarate and dry
Step 6 - weigh the DMT-Fumerate to check if all precipitated out

Cleaning excess plant oils /full spectrum elements from final yield (Note that full spectrum elements are said to have contributing effects):

Quote:
Step 1 - Perfom an IPA boil, see above
Step 2 - Add your yellowish DMT-Fumerate to some MEK and shake
Step 3 - Decant the DMT-Fumerate (it doesn't dissolve), dispose of the MEK solution
Step 4 - Dry the DMT-Fumerate, it will be white

Converting DMT-Fumerate into DMT-Freebase
For a smokable product first clean-up the DMT-Fumerate, then:

Quote:
Option A - dry method:
Step 1 - mix 1 part DMT-Fumerate with 2 parts sodium carbonate
Step 2 - add enough water to turn it into a paste
Step 3 - spread it out and let it dry completely
Step 4 - dissolve it in acetone and filter solids (redo 3x), discard solids
Step 5 - evaporate the acetone dry, leaving behind the DMT

Option B: wet method:
Step 1 - add 20g sodium carbonate to 50ml warm water and mix well (you won't use all of this)
Step 2 - let the solution cool off in the fridge, then filter out any excess solidified sodium carbonate
Step 3 - put DMT-Fumarate in a glass container, add some near boiling water to dissolve it
Step 4 - add a small amount of the sodium carbonate saturated solution until it starts clouding
Step 5 - keep adding until no more clouding or color changes occur, then add a bit more for good measure
Step 6 - store in the fridge of 3-5 days to precipitate all DMT
Step 7 - filter through a coffee filter and collect all DMT
Step 8 - put the collected DMT in fresh water to dissolve any excess sodium carbonate
Step 9 - filter the DMT out and evaporate dry at room temperature

Converting DMT-Freebase into DMT-Fumarate
For oral use.

Quote:
Step 1 - dissolve 1g dirty freebase DMT in 10ml anhydrous acetone
Step 2 - filter with a small bit of cotton in a funnel, discard any solids
Step 3 - add 600mg Fumaric acid to 100ml anhydrous acetone (FASA) and make sure all dissolves
Step 4 - add 50ml FASA to the DMT Acetone solution, wait for the clouding to settle
Step 5 - add additional FASA dropwise until no more clouding forms
Step 6 - separate the solids (DMT-Fumerate) by decanting, discard all liquid
Step 7 - wash the DMT-Fumerate with fresh anhydrous acetone (dissolves excess Fumaric acid)
Step 8 - filter the DMT-Fumerate and dry at room temperature

Note: IPA can be used instead of Acetone.

Converting Sodium Bicarbonate into Sodium Carbonate
For if you can't find pure food grade Sodium Carbonate.

Quote:
Step 1 - weigh your sodium bicarbonate, and put it onto a non-aluminum pan or oven-safe dish
Step 2 - place in the oven at 400 F (200 C) for one hour to one hour and a half to release CO2 and water
Step 3 - alternatively you can put in a stainless steel pot (no other material!) on the stove for for 20mins
Step 4 - let it cool down and compare the weight to before

Note: the resulting material should have lost around 20% of the original mass. If it didn't, leave it for longer in the oven.

Making anhydrous solvents
To make a solvent anhydrous you add a desiccant (drying agent). A common desiccant is Calicium Chloride. Another one is Anhydrous Magesium Sulfate (MgSO4) which can be made by heating Epson Salts (Magnesium Sulfate Heptahydrate) above 200 C. Anhydrous MgSO4 can absorb 204.7% of it's weight in water. 50g can absorb around 100ml water.

Quote:
Step 1 - Heat magnesium sulphate on an aluminum foil in the oven for 2 hours at 200 C
Step 2 - if you oven allows it, increase temp to 250 C for the final 30 minutes
Step 3 - take out and weigh the magnesium sulphate, it should be around half the original weight
Step 4 - store the anhydrous magnesium sulphate in an air tight container
Step 5 - take 50 grams of your anhydrous magnesium sulphate and pour it into a 0.5 liter container
Step 6 - add the solvent, shake vigorously for a few minutes, let it settle for 24 hours
Step 7 - the magnesium sulphate will absorb all of the water and sink to the bottom of the can
Step 8 - use a glass pipette to extract the anhydrous solvent, stay away from the bottom
Step 9 - discard the remaining solvent when the volume nears the MgSO4 layer

FASX Teks
A good way to start is using Cyb's ATB tek, followed up by "Spice Extraction - The FASA Approach". Base with Calcium Hydroxide or Sodium Carbonate. Lye can be used, but is not necessary. Pull with d-Limonene, Xylene or Toluene. Salt out with FASX.

- Spice Extraction - The FASA Approach" (A/B tek of choice, xylene/toluene, FASA)
- The FASA Method" (A/B tek of choice, NPS of choice, FASA)
- The FASA Method: A Summary - DMT Fumarate and Beyond (CASA, acetone, FASA)
- Amor fatis Nontoxic Approach to Spice Extraction" (dry A/B, d-limonene, FASW)
- BLAB The Big Leisurely AB" (A/B, d-limonene, FASI or FASW)
- Jorkests D Limonene and Fumaric acid Approach" (STB, d-limonene, FASW)


Eco Teks

To counter the disadvantages of using chemicals there are eco friendly teks which use household food-grade products only. The best of these is endlessness post "Extracting DMT with ethanol, vinegar and sodium carbonate":

Quote:
Step 1 - mix Mimosa powder with sodium carbonate @ 1:1 ratio
Step 2 - add water to make a paste, spread it in a wide dish and let it dry
Step 3 - do 3x 1 hour pulls with 95% ethanol (200ml pulls for 100g bark)
Step 4 - evaporate the ethanol dry
Step 5 - redissolved reddish/brownish wax in warm white vinegar, filter it
Step 6 - mix the vinegar with excess sodium carbonate, spread it on a plate and let it dry
Step 7 - pull with ethanol again, filter, evaporate
Step 8 - check purity and repeat cycle if needed

Tips
- IPA / acetone can be used if grain alcohol can't be found.
- Some users reports good results with Calcium Hydroxide (lime) as it's less soluble in water /ethanol than sodium carbonate.
- One user had a white powder precipitate out of his lime /IPA solution after several days. Filtering resulted in cleaner yield.
- Another option is to freeze the sodium carbonate /ethanol solution to -20 deg C. At this temp all excess sodium carbonate will precipitate.
- Citric acid can be used instead of vinegar, said to result in a cleaner product.

Bases
- Sodium Hydroxide 'NaO' (lye) - soluble in water and ethanol, very high pH with little water, not food safe
- Potassium Hydroxide 'KOH' - soluble in water and ethanol, very high pH with little water, not food safe
- Calcium Hydroxide 'Ca(OH)2' (lime) - poorly soluble in water, not soluble in ethanol, food safe
- Sodium Carbonate 'Na2CO3' (washing soda) - soluble in water, poorly soluble in ethanol, food safe
- Sodium Bicarbonate 'NaHCO3' (baking soda) - should be changed to sodium carbonate by heating

Eco Teks
- endlessness: Extracting DMT with ethanol, vinegar and sodium carbonate