Family: Tryptamines and MAOI/RIMA
Ayahuasca (pronounced ayawaska, or ajawaska in the Quechua language) is a traditional brew of various psychoactive infusions or decoctions, prepared with the Banisteriopsis caapi vine (or related vines). It is usually mixed with the leaves of dimethyltryptamine (DMT)- containing species of shrubs from the genus Psychotria. The caapi vine alone can induce some psychoactive effects (see Harmalas), but DMT-containing plants (such as Psychotria) remain inactive when drunk as a brew without a source of monoamine oxidase inhibitor (MAOI or RIMA), such as B. caapi.
Outside of this traditional context, Ayahuasca analogues are commonly made of harmaloid containing plants such as caapi vine or syrian rue and DMT-containing plants such as Mimosa tenuiflora root bark, Acacia species, or Psychotria species. Combining the extracts of these plants is known as Pharmahuasca.

Duration of effects can be between one and five hours with after effects lasting up to a day.

Low Dose Medium Dose High Dose
Pupils slightly dilated, slurred speech, tear forma- tion, yawning Pupils greatly dilated, slurred speech, incoherence, trembling, ataxia (physical drunkenness) Pupils greatly dilated, strong incoherence (in- ability to form sentences), sweating, ataxia, diar- rhea, vomiting, crying and laughing at the same time

Low Dose Medium Dose High Dose
Colors appear brighter, edges sharper. Light- headedness, altered thought-processes/internal dialog. Closed-eye visuals (patterns, colors) (Geometric) patterns ap- pear on uniform surfaces, walls seem to be breath- ing. Patterns and struc- tures may seem to shift or move. Things may ap- pear novel or more won- drous, events more intense. Difficulty in understanding how things work (e.g. Com- puters, phones, etc.). Dif- ficulty in following conver- sations. Loss of sense of time. Intensification of pre- existing emotions. Closed eye visions. Euphoria Geometric 3-dimensional patterns appear, difficulty in focusing the eyes, synesthe- sia, visions, intensification of emotions, insights, time dilation, mystical experiences/epiphanies/ego- death, nausea, entity contact.