Bufotenin is a naturally occurring psychedelic, present in many species of plants (most commonly in the seeds of Anadenanthera species) and Bufo Alvarius toad venom. It is said to be similar in effects to, though less potent than, 5-MeO-DMT. Chemically it is 5-Hydroxy- NN-Dimethyltryptamine.
Traditionally, seeds containing this substance are used in snuffs in various countries in South America in order to induce visionary states. Contemporary use is rare, since experiences are said to be strange and are often accompanied by nausea and unpleasant bodily sensations such as pressue in the head and stomache, constriction in the legs, tingling and burning sensations in the face, and high blood pressure.