|Entheogen||Threshold||Standard1 dose- range per body weight||Standard|
|Ayahuasca: B. caapi Psychotria viridis||75 - 100 g 30 g|
|Cannabis smoked Cannabis oral||33 mg||50-70 mg 60-80 mg|
|DMT vaporized DMT freebase oral2 RIMA3 (rue extract)||5-10 mg 20-35 mg 100-200+ mg||15-20 mg 50-70 mg 100-200+ mg|
|LSD||20 ug||1.14-1.43 ug /kg||80-150 ug|
|MDMA HCL||30 mg||1-1.78 mg / kg||70-125 mg|
|Mescaline HCL||100 mg||180-350 mg|
|Psilocybin Whole mushrooms (cubensis, dried)||3-4 mg 0.25g||0.22-0.43 mg / kg||15-30 mg|
|Salvia regular leaf, dry||0.25 g||0.5 g|
1Standard dose ranges refer to either 1) doses that have been used in clinical trials and have been found to be well tolerable or
2) doses that have been found to be well tolerable by the community of travelers, when no clinical studies were available with information.
2Oral doses of DMT depend highly on inhibition of the monoamino oxidase, and vary greatly from person to person.
3RIMA doses given are what is considered full or close to full inhibition. This can greatly vary from person to person. It is advised to try raising the dose of RIMA first before raising the amount of DMT if you find your experience was weaker than expected.
4Michael Mithoefer. “MDMA-Assited Psychotherapy in the Treatment of Posttraumatic Stress Dissorder (PTSD)”. In: ().
5Vollenweider, “Neurobiology of Psychedelics”.